ID A0A3M0L0Y2_HIRRU Unreviewed; 935 AA.
AC A0A3M0L0Y2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Groucho/TLE N-terminal Q-rich domain-containing protein {ECO:0000259|Pfam:PF03920};
GN ORFNames=DUI87_03807 {ECO:0000313|EMBL:RMC19202.1};
OS Hirundo rustica rustica.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Sylvioidea; Hirundinidae;
OC Hirundo.
OX NCBI_TaxID=333673 {ECO:0000313|EMBL:RMC19202.1, ECO:0000313|Proteomes:UP000269221};
RN [1] {ECO:0000313|EMBL:RMC19202.1, ECO:0000313|Proteomes:UP000269221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chelidonia {ECO:0000313|EMBL:RMC19202.1};
RC TISSUE=Blood {ECO:0000313|EMBL:RMC19202.1};
RA Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT "A high quality draft genome assembly of the barn swallow (H. rustica
RT rustica).";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the WD repeat Groucho/TLE family.
CC {ECO:0000256|ARBA:ARBA00005969}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMC19202.1}.
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DR EMBL; QRBI01000095; RMC19202.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M0L0Y2; -.
DR STRING; 333673.A0A3M0L0Y2; -.
DR Proteomes; UP000269221; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR005617; Groucho/TLE_N.
DR InterPro; IPR009146; Groucho_enhance.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR10814; TRANSDUCIN-LIKE ENHANCER PROTEIN; 1.
DR PANTHER; PTHR10814:SF29; TRANSDUCIN-LIKE ENHANCER PROTEIN 1; 1.
DR Pfam; PF03920; TLE_N; 2.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR01850; GROUCHOFAMLY.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000269221};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 134..195
FT /note="Groucho/TLE N-terminal Q-rich"
FT /evidence="ECO:0000259|Pfam:PF03920"
FT DOMAIN 245..273
FT /note="Groucho/TLE N-terminal Q-rich"
FT /evidence="ECO:0000259|Pfam:PF03920"
FT REPEAT 735..776
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 777..818
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 142..169
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 315..357
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..435
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 935 AA; 103747 MW; 5A67D88D675BEB75 CRC64;
MERERRERRG RGEERRRRGE ERRGEEEERR GERGEERRGE ERRGEERRGE ERRGEERRGE
ERRGEERRGE ISLAVLKRIA KYSDICTANH DYSTVCVIMM WFSAIEAQGF FKGEGMREVK
TLMMTPHQAA GQPFKFTIPE SLDRIKEEFQ FLQAQYHSLK LECEKLASEK TEMQRHYVMY
YEMSYGLNIE MHKQIISDDS VMAKSATLTF PPQWITVLHV VNGRKLIFSF QEEFSVVLGF
LKSLESHQQQ VAQAVERAKQ VTMAELNAII GIFDAVSHFL MKFKEANEKI DYVPLERNMI
MKLNTSNSLL VPDSLRSTDK RRNGPEYAND IKKRKVDDKD SSHYDSDGDK SDDNLVVDVS
NEDPSSPRAS PTHSPRENGI DKTRLLKKDA SSSPASTASS GSSTSLKSKE MGLHEKASTP
VLKSSTPTPR GDVPTPGTSA TPGLRPGLGK PPTMDPLVNQ AAAGLRTPLA VPGPYPAPFG
MVPHAGMNGE LTSPGAAYAS LHNMSPQMSA AAAAAAVVAY GRSPMVGFDP PPHMRVPGIP
PNLAGIPGGK PQEKIMFPPF QRTLLVPPKS VLTSVLRSAN DLLVTKMCSL LKTHLDMNMW
CLSPELFCFD AFKYALDYGQ MQPVPFPPDA LIGPGIPRHA RQINTLNHGE VVCAVTISNP
TRHVYTGGKG CVKVWDISQP GNKSPVSQLD CLNRDNYIRS CKLLPDGCTL IVGGEASTLS
IWDLAAPTPR IKAELTSSAP ACYALAISPD SKVCFSCCSD GNIAVWDLHN QTLVRQFQGH
TDGASCIDIS NDGTKLWTGG LDNTVRSWDL REGRQLQQHD FTSQIFSLGY CPTGEWLAVG
MESSNVEVLH VNKPDKYQLH LHESCVLSLK FAYCGKWFVS TGKDNLLNAW RTPYGASIFQ
SKESSSVLSC DISVDDKYIV TGSGDKKATV YEVIY
//
