ID   A0A3M2KT65_9NOCA        Unreviewed;       413 AA.
AC   A0A3M2KT65;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Beta-ketoacyl-ACP synthase II {ECO:0000313|EMBL:RMI28124.1};
DE            EC=2.3.1.179 {ECO:0000313|EMBL:RMI28124.1};
GN   ORFNames=EBN03_31570 {ECO:0000313|EMBL:RMI28124.1};
OS   Nocardia stercoris.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=2483361 {ECO:0000313|EMBL:RMI28124.1, ECO:0000313|Proteomes:UP000279275};
RN   [1] {ECO:0000313|EMBL:RMI28124.1, ECO:0000313|Proteomes:UP000279275}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEAU-LL90 {ECO:0000313|EMBL:RMI28124.1,
RC   ECO:0000313|Proteomes:UP000279275};
RA   Ling L.;
RT   "Isolation from cow dung.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism; mycolic acid biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004796}.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC       synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC       ECO:0000256|RuleBase:RU003694}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMI28124.1}.
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DR   EMBL; RFFH01000025; RMI28124.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M2KT65; -.
DR   OrthoDB; 9808669at2; -.
DR   UniPathway; UPA00915; -.
DR   Proteomes; UP000279275; Unassembled WGS sequence.
DR   GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR   CDD; cd00834; KAS_I_II; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR000794; Beta-ketoacyl_synthase.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
DR   PROSITE; PS52004; KS3_2; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000313|EMBL:RMI28124.1};
KW   Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW   Reference proteome {ECO:0000313|Proteomes:UP000279275};
KW   Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:RMI28124.1}.
FT   DOMAIN          9..412
FT                   /note="Ketosynthase family 3 (KS3)"
FT                   /evidence="ECO:0000259|PROSITE:PS52004"
SQ   SEQUENCE   413 AA;  42319 MW;  25EEBD87D47D81D4 CRC64;
     MTVATDTQMR DVVVTATAAT TALAPDLDGT WSALVAGESG IRALDDDFVV RYNLPVRIGG
     KLREHPAAHL SRIEQRRHSY VQQLALVLAR QVWQSAGAPE VDPQRLAVSI GTGLGGGDAL
     VSALEALNTG GYRTVSPLTV PMVMPNGPAA RVGLEIGAKA GVFAPTSACA SGAEAIAHAW
     RLIATGAADI VVAGGVEGYI EALPIAGFAM MRALSTRNDD PRGACRPFDR NRDGFVFGEA
     GALLVLESAE FAAARGARVH GRVLGAGITS DGYHITGTDP DGDGSARAMR AAIAAAGLTP
     ADIQHVNAHA TGTPVGDSSE ARAIAEVTPH AAVYAPKGAL GHSVGAVGAL EALLALNALR
     DGIIPPTLNF EQHDGAVDID VVHGTARREP LTYGLSNSFG FGGHNVSLAL GRP
//