ID A0A3M2L0A0_9NOCA Unreviewed; 406 AA.
AC A0A3M2L0A0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Sigma-70 family RNA polymerase sigma factor {ECO:0000313|EMBL:RMI29933.1};
GN ORFNames=EBN03_24400 {ECO:0000313|EMBL:RMI29933.1};
OS Nocardia stercoris.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=2483361 {ECO:0000313|EMBL:RMI29933.1, ECO:0000313|Proteomes:UP000279275};
RN [1] {ECO:0000313|EMBL:RMI29933.1, ECO:0000313|Proteomes:UP000279275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEAU-LL90 {ECO:0000313|EMBL:RMI29933.1,
RC ECO:0000313|Proteomes:UP000279275};
RA Ling L.;
RT "Isolation from cow dung.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC {ECO:0000256|ARBA:ARBA00010641}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMI29933.1}.
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DR EMBL; RFFH01000012; RMI29933.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M2L0A0; -.
DR OrthoDB; 9780299at2; -.
DR Proteomes; UP000279275; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR046531; DUF6596.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR47756:SF2; BLL6612 PROTEIN; 1.
DR PANTHER; PTHR47756; BLL6612 PROTEIN-RELATED; 1.
DR Pfam; PF20239; DUF6596; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF08281; Sigma70_r4_2; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000279275};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..77
FT /note="RNA polymerase sigma-70 region 2"
FT /evidence="ECO:0000259|Pfam:PF04542"
FT DOMAIN 109..159
FT /note="RNA polymerase sigma factor 70 region 4 type 2"
FT /evidence="ECO:0000259|Pfam:PF08281"
FT DOMAIN 178..277
FT /note="DUF6596"
FT /evidence="ECO:0000259|Pfam:PF20239"
SQ SEQUENCE 406 AA; 43751 MW; BD732E3ACB4F2863 CRC64;
MNAGDAAIAA VFAEQYGRAV ASLIRVFGDV DLAEDAVQDA FTIALRRWPE DGTPPSPAGW
IITTARRRAV DRVRREAVRR DKYAQSVLLR APDEPDDHDD LPDDRLRLIF TCCHPALART
AQVALTLRLV GGLTTTEIAH AFLVPESTLA QRITRAKGKI RDAAIPYRVP SGPELPARLA
AVSTVVYLIF TEGHTATAGD RLARADLCAE AIRLGRALTE LLPGEPEVQG LLALMVLTDS
RRAARTTPDG ALVPLARQDR GRWDRDSIEE GLALVRACLR GNRPGPLQIQ AAINAVHAVA
ADAADTDWAQ ILALYDQLTV FDPGPIVALN RAVALAEVRG PGEALAVVEG LDLGAHHLFH
AVRADLLRRL GRTAAAAQAY DAAAVLARNR AERGFLLEQS ARIRKG
//
