ID   A0A3M2L6M5_9NOCA        Unreviewed;       668 AA.
AC   A0A3M2L6M5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=SDR family oxidoreductase {ECO:0000313|EMBL:RMI32183.1};
GN   ORFNames=EBN03_14350 {ECO:0000313|EMBL:RMI32183.1};
OS   Nocardia stercoris.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=2483361 {ECO:0000313|EMBL:RMI32183.1, ECO:0000313|Proteomes:UP000279275};
RN   [1] {ECO:0000313|EMBL:RMI32183.1, ECO:0000313|Proteomes:UP000279275}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEAU-LL90 {ECO:0000313|EMBL:RMI32183.1,
RC   ECO:0000313|Proteomes:UP000279275};
RA   Ling L.;
RT   "Isolation from cow dung.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMI32183.1}.
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DR   EMBL; RFFH01000005; RMI32183.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M2L6M5; -.
DR   OrthoDB; 9810734at2; -.
DR   Proteomes; UP000279275; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd05263; MupV_like_SDR_e; 1.
DR   CDD; cd05233; SDR_c; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR44196; DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B; 1.
DR   PANTHER; PTHR44196:SF5; POSSIBLE MULTI-FUNCTIONAL ENZYME WITH ACYL-COA-REDUCTASE ACTIVITY ACRA1; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SMART; SM00822; PKS_KR; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000279275}.
FT   DOMAIN          6..229
FT                   /note="Thioester reductase (TE)"
FT                   /evidence="ECO:0000259|Pfam:PF07993"
SQ   SEQUENCE   668 AA;  71824 MW;  6AB134C6B22F33D5 CRC64;
     MVSYVVTGGT GFLGRRVVAG LLADDPHAVV HVLVREASVA KLDELAATWG ATDRVFALVG
     DLTSPDLGLA DTPPAADHVV HLGAVYDMTA SEESARAANV DGTTAVIALA RTLGARLHHV
     SSVAVAGDYT GLWFEHDFDL GQNLTSPYHR TKFEAERLVR ESPDLSWRIY RPAIIVGDSR
     TGEMDKIDGP YYFFPAIARM AALPSELPLP LPNPGTTNIV PVDWVAAAMV RLITTAGLEG
     RTFHLTDPRQ QQFTDVYRAF ARAAGAPTGI GTLPGSRAAL RLLGRVPGTT AARDLVLRGN
     GIPAEVAPHL TFNARFVSDS TQVYLSGLEV PPLESYADKL WNYWREHLDP DRARRHRDGD
     PLRDRVVLIT GASSGIGLAT AHAVAARGAT VLMVARNPED LSAAAAEVRA DGGAAQEYSC
     DITDEKAVEL LVKQVLADHG RVDYVVNNAG RSIRRSVLAS TDRMHDFERT MAVNYFGAVR
     LILALLPAMR ERRFGHFVNI SSIAVQTKVP RFAAYVASKS ALDTFSDVAA VENADAGITF
     TSVRMPLVRT PMIAPTEAYR SIPVHSPEQA AQLVVRALED RPARIDTPIG TFAQFLETVL
     PSVRKTVLQQ GFRLSGDSAA ARGERPAAAS APLERPGALQ RLAPLVQPLM SLPAPAAQLT
     NVIPGLSW
//