ID A0A3M2LEP1_9ACTN Unreviewed; 172 AA.
AC A0A3M2LEP1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=TetR/AcrR family transcriptional regulator {ECO:0000313|EMBL:RMI35991.1};
GN ORFNames=EBO15_39875 {ECO:0000313|EMBL:RMI35991.1};
OS Actinomadura harenae.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=2483351 {ECO:0000313|EMBL:RMI35991.1, ECO:0000313|Proteomes:UP000282674};
RN [1] {ECO:0000313|EMBL:RMI35991.1, ECO:0000313|Proteomes:UP000282674}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEAU-Ht49 {ECO:0000313|EMBL:RMI35991.1,
RC ECO:0000313|Proteomes:UP000282674};
RA Hu J.;
RT "Isolation from soil.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMI35991.1}.
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DR EMBL; RFFG01000153; RMI35991.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M2LEP1; -.
DR OrthoDB; 3173376at2; -.
DR Proteomes; UP000282674; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR025996; MT1864/Rv1816-like_C.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF257; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF13305; TetR_C_33; 1.
DR Pfam; PF00440; TetR_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000282674};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..54
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 17..36
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 172 AA; 17911 MW; 7ED8A8F93FE8878B CRC64;
MDAAVAAIEE SGPSGWSLRE LARRAGVSHA APAHHFGDKT GLLTALAAEG FDLLSSALTA
AGDDLLDLGV AYVRFAAEHR AYFEVMFRPE LYRADDPDLD AARTRTGGLL DRAVRPLSPG
PGPEPDPDSV LAAWSIAHGF AGLWLSGALP PELGSDPEAA ARPVLGKLFA GS
//
