ID   A0A3M2LKK4_9ACTN        Unreviewed;       253 AA.
AC   A0A3M2LKK4;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Helix-turn-helix domain-containing protein {ECO:0000313|EMBL:RMI37033.1};
GN   ORFNames=EBO15_36995 {ECO:0000313|EMBL:RMI37033.1};
OS   Actinomadura harenae.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=2483351 {ECO:0000313|EMBL:RMI37033.1, ECO:0000313|Proteomes:UP000282674};
RN   [1] {ECO:0000313|EMBL:RMI37033.1, ECO:0000313|Proteomes:UP000282674}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEAU-Ht49 {ECO:0000313|EMBL:RMI37033.1,
RC   ECO:0000313|Proteomes:UP000282674};
RA   Hu J.;
RT   "Isolation from soil.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMI37033.1}.
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DR   EMBL; RFFG01000118; RMI37033.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M2LKK4; -.
DR   OrthoDB; 3366805at2; -.
DR   Proteomes; UP000282674; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0006313; P:DNA transposition; IEA:InterPro.
DR   Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004042; Intein_endonuc.
DR   InterPro; IPR002514; Transposase_8.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF01527; HTH_Tnp_1; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000282674};
KW   Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT   DOMAIN          68..224
FT                   /note="DOD-type homing endonuclease"
FT                   /evidence="ECO:0000259|PROSITE:PS50819"
SQ   SEQUENCE   253 AA;  28498 MW;  501FDFC89D84A3AD CRC64;
     MYDPRMRQKA LELLNEGRPV AEVNRRTGIP TTTLYNWRKN LSAQFERVLA TCPRCHDRPV
     DEAAYSYLLG LYLGDGHIAH APGHKGVFRL EIACGDVWPG LIDACADALA VVMPGLKIGR
     RASPGCTNVG AYSKHWPCLF PQHGPGMKHT RKIELVPWQR AIVDRRGREF IRGLIHSDGC
     RTTNRVRRTS NSGDRRHEYP RYFFTNASDD IRKLYTDSLD ALGIAWRQNS ARNISVARAE
     AVALLDGFVG PKY
//