ID A0A3M2M1R3_9ACTN Unreviewed; 935 AA.
AC A0A3M2M1R3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=LuxR family transcriptional regulator {ECO:0000313|EMBL:RMI42823.1};
GN ORFNames=EBO15_18485 {ECO:0000313|EMBL:RMI42823.1};
OS Actinomadura harenae.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=2483351 {ECO:0000313|EMBL:RMI42823.1, ECO:0000313|Proteomes:UP000282674};
RN [1] {ECO:0000313|EMBL:RMI42823.1, ECO:0000313|Proteomes:UP000282674}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEAU-Ht49 {ECO:0000313|EMBL:RMI42823.1,
RC ECO:0000313|Proteomes:UP000282674};
RA Hu J.;
RT "Isolation from soil.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMI42823.1}.
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DR EMBL; RFFG01000030; RMI42823.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M2M1R3; -.
DR OrthoDB; 3178131at2; -.
DR Proteomes; UP000282674; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000282674}.
FT DOMAIN 874..935
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
FT REGION 853..881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 935 AA; 100833 MW; 799C796AC4CE813E CRC64;
MTLIEREQEM ALLAGLLDDC ARGRGSAVLI SGAVGSGRTE LLHAFTESAV GSGAHFLRAT
AAPEQSAVPF GIVDQLFATA VSVPGHGDRI AGLLESPDFL AALDDVAEDP TGYAAARIQR
RLGRELAEIT RDAPLIIGVD DVQHSDALSF EWLRRLMWEP RVPRVMLVLT ERFPPSGDRP
IPPVELLRES RYHRVRIGPL SEGGVTKMIG RYLDERSVRR VASEVHQVSG GNPLLVRTIL
ADSGVRLTWR PERESLESVT AGPMFRLAVL RCLDRSGAAI RTAARVLATL GPSTTPELLD
RMLETVPAGS AGRALEALTS AGLVEGHEFR HPEAHAAVLS NLAAEERASL HRRAARLLDE
SGADAGTVVR HLPVEFAGRD SWTVSMFEAA AAQAFREGRR DAALAHMDAA LDLCGDARRE
VELTLTMIRM SGPARITVLR RHIDRLTEAV ADGTLGGRRA AEIVKAALWF GRLDAAVAAA
TTLLASDDAD ELLHCRAWLS VAFPTFAERF AELRGGDGGG DGHADPGGSR PRAARALEEA
VRGGDPAAVM GATERLRDQR IDQSTFEPIT QALLALTYSG RLAEAARWCD ELFEQVTAAE
QPAWYCYLVG ARARISLRQG DLPRARQLAL SALTTSVPGA LGVGVGGQIA VVVMASSLMG
RPEEAAEWLG RELDDLVFQT PFGLEYLHAR GHHYLLTGRP NAAVEDFLRC GELLARWGMD
TPRVLPWRTS AAEACLAAGA EKRARELVEE QRARLAPGPG LARGAVLRLS AAMSKPGVRL
GELREAVDVL ESAGERIELV KAMAGLGETY YKLGDPSRSR VILQRAWELA NACGAGALSA
RFDHAVYQRP HESVGTAKER RRGVMAGGAG GAGAGDRTGE LSEAERRVAR LASQGYTNRQ
IGERLYISVS TVEQHLTRVY RKLAVRHRTE IPSTV
//
