ID   A0A3M2M716_9ACTN        Unreviewed;       838 AA.
AC   A0A3M2M716;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=ABC transporter permease {ECO:0000313|EMBL:RMI45351.1};
GN   ORFNames=EBO15_10540 {ECO:0000313|EMBL:RMI45351.1};
OS   Actinomadura harenae.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=2483351 {ECO:0000313|EMBL:RMI45351.1, ECO:0000313|Proteomes:UP000282674};
RN   [1] {ECO:0000313|EMBL:RMI45351.1, ECO:0000313|Proteomes:UP000282674}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEAU-Ht49 {ECO:0000313|EMBL:RMI45351.1,
RC   ECO:0000313|Proteomes:UP000282674};
RA   Hu J.;
RT   "Isolation from soil.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC       {ECO:0000256|ARBA:ARBA00038076}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMI45351.1}.
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DR   EMBL; RFFG01000014; RMI45351.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M2M716; -.
DR   OrthoDB; 9780560at2; -.
DR   Proteomes; UP000282674; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR003838; ABC3_permease_dom.
DR   InterPro; IPR025857; MacB_PCD.
DR   PANTHER; PTHR30572; MEMBRANE COMPONENT OF TRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR30572:SF18; MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF02687; FtsX; 2.
DR   Pfam; PF12704; MacB_PCD; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000282674};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        249..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        293..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        346..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        389..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        422..444
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        481..501
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        710..738
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        765..789
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        801..820
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          17..175
FT                   /note="MacB-like periplasmic core"
FT                   /evidence="ECO:0000259|Pfam:PF12704"
FT   DOMAIN          251..370
FT                   /note="ABC3 transporter permease protein"
FT                   /evidence="ECO:0000259|Pfam:PF02687"
FT   DOMAIN          477..683
FT                   /note="MacB-like periplasmic core"
FT                   /evidence="ECO:0000259|Pfam:PF12704"
FT   DOMAIN          717..830
FT                   /note="ABC3 transporter permease protein"
FT                   /evidence="ECO:0000259|Pfam:PF02687"
SQ   SEQUENCE   838 AA;  85872 MW;  35CC233846AF402C CRC64;
     MLKTTVAGLA RQKLRLLLTA LAITLGVGFI TGTFVLTDSM KSGVDKTFAK SADKIDVAVL
     PKRAADDLPP ALLAKVKGVP GVTDAEGLVK GDAALVGRDG KAVGDSPTLG MSMPSGRLLR
     YELNGGRTPN GPSEAVLDTR LAKREQFKVG DAVTVLDHKN KPHRFTVVGL VDMGMDAEAS
     FRGAVGFDAA TTTAMTGVKS FSEIDVLGGG RDAVASAAGP AYDTLTSKAL AQRLAKSNGA
     DTTVIQTGLL LFGLVAMLVS ALVIYNTFAI LIAQRMREMA LLRCVGATRR QVFGGVLTEA
     VVVGFVGSLL GLAAGLGLGA GALAVIGSFD TGIKLAGPAL TVRTVLVALL VGVVVTVVSA
     LVPARAATRV APVAALRADL EPGSGTFRLG WVRTVLTALF GVVGVGLAGY GGFGSAKGES
     AMYMVALGGM LFFLAVVAAM PALVRPLGRV IGALPAKTGG VPARLAVENA RRSPRRTATT
     TIALTIGIGL MSLFSVVAAS GSATVNAQLD KHFPVDFQVQ SQFGDSKSAA DEASRRVPSS
     LVADLRALPQ LGEVTAAREA GRPKSGHRDT TVTTVTESAF GSMIKLGTVK GSVAAPKPGT
     LIVDKDTARD KHYQVGQTVQ VRGDRGVLPL TVAGVFSGDV PLRGVLIGPA DFARVSAVQD
     AATVWAKTKP GVQVDEARGA VDAATKAYPT IRVGSMAEMR DQFGKAVNTL LMVFGGLLGL
     AIVIALFGIA NTLSLSVVER TRESALLRAL GLTRRQLRRM LSVEALVMAV IGAVTGIVLG
     VGFGAAATYS MSDSAVFAVP YAQIIGFVVL AAVAGVLAAV MPARRAAKAS VVESLSSG
//