ID   A0A3M2RJ78_9HYPO        Unreviewed;       696 AA.
AC   A0A3M2RJ78;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Sodium-dependent serotonin transporter {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CDV36_014027 {ECO:0000313|EMBL:RMJ05294.1};
OS   Fusarium kuroshium.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium solani species complex.
OX   NCBI_TaxID=2010991 {ECO:0000313|EMBL:RMJ05294.1, ECO:0000313|Proteomes:UP000277212};
RN   [1] {ECO:0000313|EMBL:RMJ05294.1, ECO:0000313|Proteomes:UP000277212}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCR3666 {ECO:0000313|EMBL:RMJ05294.1};
RA   Stajich J.E., Carrillo J., Kijimoto T., Eskalen A., O'Donnell K.,
RA   Kasson M.;
RT   "Comparative genomic analysis of Ambrosia Fusariam Clade fungi.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMJ05294.1}.
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DR   EMBL; NKUJ01000421; RMJ05294.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M2RJ78; -.
DR   STRING; 2010991.A0A3M2RJ78; -.
DR   Proteomes; UP000277212; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd11554; SLC6sbd_u2; 1.
DR   InterPro; IPR000175; Na/ntran_symport.
DR   InterPro; IPR037272; SNS_sf.
DR   PANTHER; PTHR11616:SF279; SODIUM-DEPENDENT SEROTONIN TRANSPORTER; 1.
DR   PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR   Pfam; PF00209; SNF; 2.
DR   PRINTS; PR00176; NANEUSMPORT.
DR   SUPFAM; SSF161070; SNF-like; 1.
DR   PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277212};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        40..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        112..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        215..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        265..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        298..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        354..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        394..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        431..449
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        461..482
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        488..506
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        556..578
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        590..611
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          667..696
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        668..696
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   696 AA;  75890 MW;  AE9C626F52EF30BB CRC64;
     MAKAEGGPKP GLAKRIFLLL APDSAKDDDG RDNFNSRSQF VLCAMGGAVG LGNLLRFPSV
     VFNNYGLQFF IPYAVALFLI GIPILLLEIT LGQAYRGGCV TAWNNVNHRA KGIGLSMVFN
     GFSVVGYYVP ILAWAMTYFR LSFKSPLPWA GGDTVDFFLN EVVRNVSPTG GDEDGGGLKS
     YPGRGIIGET FGWGIMIWFV TWMCTFKGVG LTGRVIYITM ALPLVMIGIL AIRSLSLPDA
     SNGFKLYVGM WRSESLEGPR VWQDAFGQMF FSIGVGFGYF TSYASYNNKF ANAVQDAFII
     ALSNSAIEII SALAVMGVVG FLGINPGEVD PLSTFSSGFF YYPEALAQMP GSNFFSALFF
     ITLVLLGLTC VFALAEVLVT LLCDTDLGQR VPRWVISTSV IILGALTSLI YSSEFGFNTL
     DAVDMFVNDV ALFITVWSET YMACTLYRWR DPVDQIGPIS YFAYNGGYVL ATFLGILLGH
     LVNPSVGAGV GFGVFIAGSL IAAFVGKTPT VPAPRFWGGN PILSRFWYAA FYSGNQLRRD
     LNRAILGGSK NWKIHWVWPI CLKYITGPAV ALVFSFAYPK FLNGHADDPP FIYSFVLMHF
     VVIFIVGAFI VPRFLNILIP AHRVARGDGK YEVAPQITVG ETPVINDGGL EGGNVLEGDI
     AYHNSADRSS ADADKAVQRN DATMSEREPA FVERKQ
//