ID   A0A3M2SBV1_9HYPO        Unreviewed;      1192 AA.
AC   A0A3M2SBV1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Homeobox protein 4 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CDV36_005352 {ECO:0000313|EMBL:RMJ14969.1};
OS   Fusarium kuroshium.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium solani species complex.
OX   NCBI_TaxID=2010991 {ECO:0000313|EMBL:RMJ14969.1, ECO:0000313|Proteomes:UP000277212};
RN   [1] {ECO:0000313|EMBL:RMJ14969.1, ECO:0000313|Proteomes:UP000277212}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCR3666 {ECO:0000313|EMBL:RMJ14969.1};
RA   Stajich J.E., Carrillo J., Kijimoto T., Eskalen A., O'Donnell K.,
RA   Kasson M.;
RT   "Comparative genomic analysis of Ambrosia Fusariam Clade fungi.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00108}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMJ14969.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NKUJ01000073; RMJ14969.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M2SBV1; -.
DR   STRING; 2010991.A0A3M2SBV1; -.
DR   Proteomes; UP000277212; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR11850:SF102; HOMEOBOX PROTEIN HOMOTHORAX; 1.
DR   PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00355; ZnF_C2H2; 3.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS51253; HTH_CENPB; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000277212};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN          195..258
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DOMAIN          413..441
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          789..863
FT                   /note="HTH CENPB-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51253"
FT   DNA_BIND        197..259
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          252..282
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          342..407
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          861..884
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        261..276
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        342..379
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1192 AA;  132764 MW;  E74541D7E01EB74E CRC64;
     MATIDEMDQF VNWDKADDTV GQPFQEDALA GLTTGPDGDN IDLVLANVNE DDFSFCALQH
     FSDNNFPLPD LTTEQVMDFT TTADNLAHQF QWIMPDSPCT NCTVGGFSCK KIQEGQYKGY
     CTTCVALRVD CSFGVTAEPL NPTTTAPFGI NPWMSSETNP PNTVLEDAQD DSCQSSRNAS
     VTDLTNLTDT FNKAAPPPKI GARFSRESVR ILKNWLSTHN RHPYPSDEEK EMLQRQTGLN
     KTQITNWLAN ARRRGKVQAP RSTSPHYTSS WSGPIDIPQR RGTPALEAMN PLQRWEHSPP
     ENEPASVTAI ARAVTASSSG MSSGLNSPFS FHYTDDGSSR SLCNQSSVSS LGTSHSSNGS
     HGSAYSHGSR NSWGSFGSAP FNSRGRRRRR RRTSTKPGKE PGKTSLSAPL KTFQCTFCTE
     TFRTKHDWQR HEKSLHLSLE RWVCSPHGPR AVNPDTGVLS CVFCGEANPD DAHIESHNHS
     ACQERSPEER TFYRKDHLNQ HLRLVHNIKF QDWSMKSWKV ATPEIRSRCG FCGIIMDTWT
     IRVDHLAEHF KTGYSMADWK GDWGFDNPVL EMVENSMPPY LIHYERTSPL PYVANQPPPE
     SPRHAYELIK LEMAFFMRNY EDQHGRLPND EEMMVEGCRI IFASELLSLQ GIATRPSWLR
     DLIMSSDSLQ QKARFGPLRG AAENRLATLK INGKDNLFEE CPMEVQLQEF VKTKRLLGLT
     AMDDELQEEA CRIVGRVEEV STHPSDAIAN WLLRLAVSST HWLASFRRRA HLPRSEDVKD
     HICRSTDPLS IDSTIHSYTR LERELGDYLK LQRSMGSEPT DDDLQRQARI IIYEFDDGWN
     QTAADNMAWL ESFKARHPAT TESSPAFSLQ PSTTSTLGGT TVTNPTTTSP DCPVLQGCDS
     PFNVCNLGTS QPGPYFLNDA NCYRRLAKEL GRWVGATMSA NNPNQHVPTD AELQHQARWI
     LYDDDDPWNQ TAADNAEWLQ RFKRDAGILK TDGPGLPVSD GWALEQGGSG FAPPYACPKA
     SLEPFPANAQ VPMGQGAKSL PAAVANSYLE NLTSQAARPA MVFCSRELER GLVDYVEDHV
     SCTGRMPSDD MIKARGRQIL GANTTPAEDR DLMEKFKAMV AKKVPHALPA QEATAAAPEM
     PSNMGMNISD ADLDNILQDM NFEFDPQDFE GVTMEGLQDA GGVSLNMTGF NN
//