ID A0A3M2SI81_9HYPO Unreviewed; 3304 AA.
AC A0A3M2SI81;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=ubiquitinyl hydrolase 1 {ECO:0000256|ARBA:ARBA00012759};
DE EC=3.4.19.12 {ECO:0000256|ARBA:ARBA00012759};
GN ORFNames=CDV36_003092 {ECO:0000313|EMBL:RMJ17256.1};
OS Fusarium kuroshium.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium solani species complex.
OX NCBI_TaxID=2010991 {ECO:0000313|EMBL:RMJ17256.1, ECO:0000313|Proteomes:UP000277212};
RN [1] {ECO:0000313|EMBL:RMJ17256.1, ECO:0000313|Proteomes:UP000277212}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR3666 {ECO:0000313|EMBL:RMJ17256.1};
RA Stajich J.E., Carrillo J., Kijimoto T., Eskalen A., O'Donnell K.,
RA Kasson M.;
RT "Comparative genomic analysis of Ambrosia Fusariam Clade fungi.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMJ17256.1}.
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DR EMBL; NKUJ01000035; RMJ17256.1; -; Genomic_DNA.
DR STRING; 2010991.A0A3M2SI81; -.
DR Proteomes; UP000277212; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022099; DUF3638.
DR InterPro; IPR022105; DUF3645.
DR InterPro; IPR046541; DUF6606.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13367; UBIQUITIN THIOESTERASE; 1.
DR PANTHER; PTHR13367:SF28; UBIQUITIN THIOESTERASE ZRANB1; 1.
DR Pfam; PF12340; DUF3638; 1.
DR Pfam; PF12359; DUF3645; 1.
DR Pfam; PF20255; DUF6606; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000277212};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 27..300
FT /note="DUF6606"
FT /evidence="ECO:0000259|Pfam:PF20255"
FT DOMAIN 2102..2323
FT /note="DUF3638"
FT /evidence="ECO:0000259|Pfam:PF12340"
FT DOMAIN 2446..2478
FT /note="DUF3645"
FT /evidence="ECO:0000259|Pfam:PF12359"
FT REGION 3236..3304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 586..621
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 3247..3261
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3269..3283
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3304 AA; 374083 MW; 2380623E2D15BA86 CRC64;
MPSAIPPRTT GPVATIQHEN LSLSDALYNH LVLPPKLPHR RDPNLNEIEA DLINRLISCV
KHIRDLPDND FHSTWNTIER GLQATKIVHS SGHVDRDVLA RELNGLGEAD FVVVHVHAQN
CALFIRRAED PVLGASLVFE AFETSARNED VLATDNALKW QFPGCAVAVP LTTVQETGFV
SNLASFLDSA SREALMDFSA LAIKAGTTIA ENRNTAEPAL ISSMLMAILQ ENGRRLTPVL
LQKMVRDDVC WKSAEKPWKR LPFWLVLRVA VSRYLAQQLG GELGRAEYKF MMAHLFSEFL
SHVQHSGIQL ERLDFLKKKI CRRLVKLDVD KDRSQDRQVV QRIEYLFLHL SPGIQHSVSK
ATAFTDASWS RQKLAMTKTI PPVPRQASPN DLKFDLKVSG AHLFSIWKGW KKPVHRREDR
NGKLSIAEAA KMHLGTFSHR HHKLIKMETN LARFCIECKD SPHSTIQMAS VHIHGYLSHA
NEVYNGMPEL KSTMILNVMD LWVSMDEASC GLYPLLKEFH PVFRPEMLDV LLISNFEDMK
RLRKIQLYIQ NRIASCEGSA MTIFDDPVRG SFGHRAYDDS ELSEQLQALH ESIENWASKI
RDEKEEEWKK KSNEYAQLSQ RIDESSCVYL VDDDNPLGRG IHDPHCARCF MVRQLRRIKI
QGYEHPLPSD PYVARAVIFE LACPQSFATY RDTTWTAISR LALSPLEEGV EPKCRLRDYQ
QLQRFANVTT MKCSLASVTK PFFMTHYTEM PFPVEWDNGR NGVCRPNGLK LTYHDNLSKK
WPGRRSHLSV LHQVKLQISS SSPFAPILQD NIFLKNIYGP SSYEIMSTAS RCPQGINVHE
YLAFQTIASG KSRRWLSILT ELGSANLNFS NEATMLLLSH MALQCGPFDA SQDTLRLIHA
VFRDPDFCGT LIQQLASRLD SLSANWRETY LMETIVTFTL RLIDFTWAAK MEEITQKAIS
LLLRARGTCV RWFKLLRAEA YKVTETELAQ RFQQYALWAA LLCKRTFTHL TYRPAELDDS
SLEVYIQSSI TVHDNLVVKL EALPELLQHT VIRDMRLSYQ LSPLISEAIM QKTDIFRRSL
QEMWPEEEGC ARIFRNVKLL APHWISCLSV SGDEGFEQDV HYNITEGLLM VDLRPMGKLP
KDPKTSLILN ELFGNQSLLT FPSERPRMQY SLCVRPRGFQ VHVGFDRSGE LIVRAFRKPY
SLQLIPREMF RNGQYWDLPG PLLQGSFHWL NLNNGELLIT KSHQPWPESP SRWYTLSLSD
QTCTMARNGS GVYERDSVVN PYSPLFNRIA GIFGCFEPRE HILVRQPGGG KSLQVELPRL
NIMFFVNKNR LLQSPQLQCQ IDTNQDAGTW YGLRSKLVCT SDINPMHRSI LVLLGNLSAT
SDGCHVMVKI DSNSKHGVGK YGKFTINKAL GRIDCAPEPT LVFMKALLHA STSFLLPDPL
TGRTGTEEAI QWLQAGISQP WSPLGPPPME ILVKISKLSP RRVYYPLDLK VMRTDTWIES
LPTTLQRSEF RPIVDQILQG SMTLAMFATK DQAAMEPPEL PDYGEPHLHA RAMFRQQAVE
RYLGDACDRL VPDNKEYQSR DRPSTVNIAH RNVLEATHLI RQWPPNMRTT DNLAQMLAQG
GIVGGFEAPF QAASLSDKLK VDILQHWGSL VRFARDATDR YHLMFLLGPM SFRADANMPL
LRAIIAFSVF GELKGLDLPP WEDFCHFQPN QVPQLDYLLQ LLKPFRAPPP TSDTHALEEF
SSAKLRRKLQ LERCKHETRV EDDCKLFANH LLSQWPCLEP TVSGLSQSVL LDIGAALEVI
RPEWRRLFMN RDLTEHLQAV QEILDRKSSE DRYETPPTVP SDDAFAVRIR GNESVDLKQL
LAKPYIVVHE AVPEPAKEKI GSTERPFLTE RSFPQGLGAF GALAWLNGRG SANGQRAHSH
MLGTRGPKTD AAVFPTQKMV TESVMKLEAI STRLGTSKSA VRRRYAADFQ NSLDAFRRLD
SPTSTTTASL QTREGAIKLK SEKVNANFRN ILVSLDAEGP TCSARRIGWL KAGGQWPIVT
KATVLGKISS IASQKAFGSG MRNAIIDLGV EITKMQREIR LHDLALKDMS GRYQEEVANQ
GHSNWSPEEY PDWLLLEIES NLMIRPVQID VALATISPES GSNSVLQMNM GQGKTSCIIP
MAAAALANRK QLVRVIVPKA LLQQTAQLLQ ARLGGILGRS IRHVPFSRRT PTTETTIRAF
LSIHKEMLKS AGVMICQPEH NMSFMLSGQQ RLLDEKPLQA GPMIKVQEWL MRHSRDILDE
SDYTLAVRTQ LIYPSGSQMT VDGHPHRWLV AEAVLRLVDG HLGDLPYDFP HSINVMRRRG
GGFPFVFFLR QDVEDELVRR LTKDICEGAG GILPLAEQAM AAKDRVAVKD FITSARPRPA
SVERVRGMCP DKPSLRQTVY LLRGLLVNRI LMMTLKKRWN VEYGLHPRRD PIAVPFHAKG
VPSDQSEWGH PDVAILFTCL AFYYDGINPA QLRQCLEHIL KSDDPATEYD AWTKSSEGFP
SSMKAWNSIN VDDDMQLREI WKAVRYNNVV IDYFLNNFVF PRHAKQFEVK LQSNGWDIPL
SPLGDTSQQG KPSGVSKPLS TGFSGTNDNR TMLPLNIEQQ DLSSLHHTSA EVLSYLLHTR
NRHCILPIDV RTSQYGRATE MDLLHYLKRK QIRVLIDAGA QVLEMDNFTL AQQWLRIDQS
VRAALYFDEE NKPWILTQEG RRTPLLASPF ADDLSQCLVY LDEAHTRGTD LRLPPLARGA
LTLRLGQTKD HTVQAAMRLR QLGTTQSVSF FIPPEVHQSI ADLQKKTMHE PIDSSDVSIQ
WLLDNTCDNI EQLQPLYFAQ GMDFCRRMQA SINHPDFLTD KPQRKAYVQA IKQDEQQTLQ
HLYEPKLKNR ATGVQTSNND TLKQFISELT TRRKAFQDTG KAVHASALQE VEQEREVAFE
VESVRQVKKP HHYAAHSFPG LNASLEAFAR TGRLPPDSHY FNHIFHALSR TGIGRKFKVS
SKATKSKLLE TVEFSRTIKL QGELSNDNFI RPVNWVLWSP AAEIAVVIIP EEAEALIPLM
RDPDVKVATH LLIYAAPITR KMLHFNHLKY YSIPPLPSDW NAPTWLQVEL GLYSGRLYFE
WGEYEQMCSL LGIQEGPGLV EEPGLDMMVD GAADETLAQD GVQAQVQGEA QANKDPTTED
TKLAQSPLTF LQEWLALRRR GQDFAHSPMG FVSQGKWLRK DHVFFNQVEQ VAEGQDGALV
QPVMRESTDN NERRDDGYYG VDDMGANEAG DGDFSDDDIE YDESEYANSR VPDGSGADTG
HSSD
//
