ID A0A3M2SVR8_9EURO Unreviewed; 364 AA.
AC A0A3M2SVR8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 22-FEB-2023, entry version 16.
DE RecName: Full=Transcriptional activator HAP2 {ECO:0000256|RuleBase:RU367155};
GN ORFNames=PHISP_07458 {ECO:0000313|EMBL:RMJ21673.1};
OS Aspergillus sp. HF37.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1960876 {ECO:0000313|EMBL:RMJ21673.1, ECO:0000313|Proteomes:UP000272442};
RN [1] {ECO:0000313|EMBL:RMJ21673.1, ECO:0000313|Proteomes:UP000272442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HF37 {ECO:0000313|EMBL:RMJ21673.1,
RC ECO:0000313|Proteomes:UP000272442};
RA Tafer H., Lopandic K.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the sequence-specific heterotrimeric
CC transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3'
CC box motif found in the promoters of its target genes.
CC {ECO:0000256|RuleBase:RU367155}.
CC -!- SUBUNIT: Heterotrimer. {ECO:0000256|RuleBase:RU367155}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU367155}.
CC -!- SIMILARITY: Belongs to the NFYA/HAP2 subunit family.
CC {ECO:0000256|RuleBase:RU367155}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMJ21673.1}.
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DR EMBL; RAQS01000446; RMJ21673.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M2SVR8; -.
DR STRING; 1960876.A0A3M2SVR8; -.
DR Proteomes; UP000272442; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 6.10.250.2430; -; 1.
DR InterPro; IPR001289; NFYA.
DR PANTHER; PTHR12632:SF6; NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT ALPHA; 1.
DR PANTHER; PTHR12632; TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED; 1.
DR Pfam; PF02045; CBFB_NFYA; 1.
DR PRINTS; PR00616; CCAATSUBUNTB.
DR SMART; SM00521; CBF; 1.
DR PROSITE; PS51152; NFYA_HAP2_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU367155};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367155};
KW Reference proteome {ECO:0000313|Proteomes:UP000272442};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU367155};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU367155}.
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..189
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..209
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 364 AA; 38771 MW; 00930AD8CBB60AC2 CRC64;
MEYPPQYQQP HGQHPPAPSH IPGPYQAASQ NTGSAVGPMA SPSHPQAQLP QAHPSHQASP
IVPSQSHYQQ SQNAPGSVHQ PMSFPQPYGV TAAMPQTYGI SPTQAAAMAT AAASGQFYPL
HQDSMAGQMP QGPRGSPRMA GVQPKTERNP RSPPQMPGQV PMGSQVQMPQ RRMSHVGSPH
VQSAQPVLNH VGRPSVPPSM PPPSQAPVQQ GQPSPEMVAG ATEESPLYVN AKQFHRILKR
RVARQKLEEQ LRLTSKGRKP YLHESRHNHA MRRPRGPGGR FLTADEVAAM EKKQIAGGGQ
EVATSNASQP VGNPSPSARK RKSSDIIEEN ANSAKKAKTG GQPGASASAE ESEPESAEPS
DEEG
//
