ID   A0A3M2SY66_9EURO        Unreviewed;       322 AA.
AC   A0A3M2SY66;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   13-SEP-2023, entry version 14.
DE   RecName: Full=mRNA decapping hydrolase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PHISP_06659 {ECO:0000313|EMBL:RMJ22463.1};
OS   Aspergillus sp. HF37.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1960876 {ECO:0000313|EMBL:RMJ22463.1, ECO:0000313|Proteomes:UP000272442};
RN   [1] {ECO:0000313|EMBL:RMJ22463.1, ECO:0000313|Proteomes:UP000272442}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HF37 {ECO:0000313|EMBL:RMJ22463.1,
RC   ECO:0000313|Proteomes:UP000272442};
RA   Tafer H., Lopandic K.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HIT family. {ECO:0000256|ARBA:ARBA00010208}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMJ22463.1}.
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DR   EMBL; RAQS01000332; RMJ22463.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M2SY66; -.
DR   STRING; 1960876.A0A3M2SY66; -.
DR   Proteomes; UP000272442; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR   Gene3D; 3.30.428.10; HIT-like; 1.
DR   Gene3D; 3.30.200.40; Scavenger mRNA decapping enzyme, N-terminal domain; 1.
DR   InterPro; IPR008594; DcpS/DCS2.
DR   InterPro; IPR036265; HIT-like_sf.
DR   InterPro; IPR011145; Scavenger_mRNA_decap_enz_N.
DR   PANTHER; PTHR12978; HISTIDINE TRIAD HIT PROTEIN MEMBER; 1.
DR   PANTHER; PTHR12978:SF0; M7GPPPX DIPHOSPHATASE; 1.
DR   Pfam; PF05652; DcpS; 1.
DR   Pfam; PF11969; DcpS_C; 1.
DR   PIRSF; PIRSF028973; Scavenger_mRNA_decap_enz; 1.
DR   SUPFAM; SSF54197; HIT-like; 1.
DR   SUPFAM; SSF102860; mRNA decapping enzyme DcpS N-terminal domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000272442}.
FT   ACT_SITE        253
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR028973-1"
SQ   SEQUENCE   322 AA;  37013 MW;  0394537B151DA4CC CRC64;
     MSSDQKKAAE ALISRFEINR LLKQDQNGRR IALLGTIDGK QGILIAERAA FATESLESLQ
     AFRSAIARVN NLGDNDIYRW YLASSGDNGA QAQPDLKLNI IWPCTEQHVK KYSEQLVRMV
     TETPEIYRRH VRPYMSAKRE EGRLNWVFNI LEGRTEQEDV ILRDDGNGGR PEDAFLMLPD
     LNWDRKTMGS LHLLALVQRR DIWSLRDLRK RHVPWLRYLR QRVLEATVKM YPCLEQDQLK
     LYVHYQPTYY HFHVHVVNVM LEAGSTQATG KAFGLENLIS QLETIAGDED ASMADVSLTY
     FLGEASELWT DVYAPLKSNT AK
//