ID A0A3M6VF55_9STRA Unreviewed; 695 AA.
AC A0A3M6VF55;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=START domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DD237_003154 {ECO:0000313|EMBL:RQM14545.1}, DD238_005735
GN {ECO:0000313|EMBL:RMX64641.1};
OS Peronospora effusa.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Peronospora.
OX NCBI_TaxID=542832 {ECO:0000313|EMBL:RMX64641.1, ECO:0000313|Proteomes:UP000282087};
RN [1] {ECO:0000313|Proteomes:UP000282087, ECO:0000313|Proteomes:UP000286097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R13 {ECO:0000313|EMBL:RQM14545.1,
RC ECO:0000313|Proteomes:UP000286097}, and R14
RC {ECO:0000313|EMBL:RMX64641.1, ECO:0000313|Proteomes:UP000282087};
RA Fletcher K., Klosterman S.J., Derevnina L., Martin F., Koike S.,
RA Reyes Chin-Wo S., Mou B., Michelmore R.;
RT "Comparative genomics of downy mildews reveals potential adaptations to
RT biotrophy.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMX64641.1}.
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DR EMBL; QLLG01000297; RMX64641.1; -; Genomic_DNA.
DR EMBL; QKXF01000198; RQM14545.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M6VF55; -.
DR VEuPathDB; FungiDB:DD237_003154; -.
DR Proteomes; UP000282087; Unassembled WGS sequence.
DR Proteomes; UP000286097; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR CDD; cd00821; PH; 1.
DR CDD; cd00177; START; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045096; EDR2-like.
DR InterPro; IPR009769; EDR2_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR12136:SF47; ENHANCED DISEASE RESISTANCE PROTEIN (DUF1336); 1.
DR PANTHER; PTHR12136; ENHANCED DISEASE RESISTANCE-RELATED; 1.
DR Pfam; PF07059; EDR2_C; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00234; START; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50848; START; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000282087};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 200..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..114
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 253..409
FT /note="START"
FT /evidence="ECO:0000259|PROSITE:PS50848"
SQ SEQUENCE 695 AA; 78502 MW; F44281086EC8887C CRC64;
MEGWLTKRRD HMNLIWRDRY FLLDCNQLRY YRKRGDPAPR GTYILTDGCI VSSVFNSEEK
HKHHGPVWMF RITFTVGDTT TGEKQAKKDR FLDLGAKSEE NAKNWKKALE TAVRSLQELV
LHQRKLKFDS ENFPTPTYVP RMLQADEDTM SLFNLDADNV KAEQVWWLAR VEGGLRIMQE
CPLGPNVAAT LCFQHATTTN GLICSAVLGA ALSFSIMYSF AMNMLLSFMT AMMAIGVCCV
AVMPTQTPEI SSFRVSQVVH GSPTEVFRLI MNSKRFQRWD AATATMRVVQ QLDDHADIVY
VTQRPTYLWP LWQKARDLVF MRYWRREEDG SYFVMYQSMD HPECRVRHNY VRANILGGGF
VIAPQRVPGG TIRTLVTYVL RYDPGGWSRI YHQLGMDVDL VMPQLRSVVG IRDEMSATDF
ITPNVSMASA GEGEGGPEAG QEDSAVNQRT SVDSMGVVMG VQKLQTSLPE KMWAEPDASL
FSVRGHNYLN DKKKIPSGPA MFHTVGVDLL SFSSAAERYN ISSRADSVGR TSTEFTFVVN
MIIPGTENTC MVFYFHPARD NVFEDGSPFS ELLNDFFDGD DEFRNSRFKL IPTVEEGSFI
IKQSVGSKPT LLGNKLKCLY YRGDNYFEVD IDISSNSVAN TVVGMVQGVT KSLVVDMAFL
LEAQSDEELP EIILGAVRLQ HVSLDNPHRM PQLSP
//
