ID A0A3M6VLH1_9STRA Unreviewed; 668 AA.
AC A0A3M6VLH1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=DD237_001598 {ECO:0000313|EMBL:RQM17636.1}, DD238_000753
GN {ECO:0000313|EMBL:RMX67768.1};
OS Peronospora effusa.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Peronospora.
OX NCBI_TaxID=542832 {ECO:0000313|EMBL:RMX67768.1, ECO:0000313|Proteomes:UP000282087};
RN [1] {ECO:0000313|Proteomes:UP000282087, ECO:0000313|Proteomes:UP000286097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R13 {ECO:0000313|EMBL:RQM17636.1,
RC ECO:0000313|Proteomes:UP000286097}, and R14
RC {ECO:0000313|EMBL:RMX67768.1, ECO:0000313|Proteomes:UP000282087};
RA Fletcher K., Klosterman S.J., Derevnina L., Martin F., Koike S.,
RA Reyes Chin-Wo S., Mou B., Michelmore R.;
RT "Comparative genomics of downy mildews reveals potential adaptations to
RT biotrophy.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMX67768.1}.
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DR EMBL; QLLG01000158; RMX67768.1; -; Genomic_DNA.
DR EMBL; QKXF01000092; RQM17636.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M6VLH1; -.
DR STRING; 542832.A0A3M6VLH1; -.
DR VEuPathDB; FungiDB:DD237_001598; -.
DR Proteomes; UP000282087; Unassembled WGS sequence.
DR Proteomes; UP000286097; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd00821; PH; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 3.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR14336:SF8; DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE; 1.
DR PANTHER; PTHR14336; TANDEM PH DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 3.
DR SUPFAM; SSF50729; PH domain-like; 3.
DR PROSITE; PS50003; PH_DOMAIN; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000282087}.
FT DOMAIN 249..339
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 470..560
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 58..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 193..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 668 AA; 74987 MW; B2254C5E8B2FF4A4 CRC64;
MYSNEMLFQC DGSPHMVENT EMLDEDDVVS LGLAVNTRNY QALIANLACK ASVSHGRRRS
LGTMYQEDQP LESPIKDEKM APSDQKEEDY TVMGLPVDTR NYEAIVGGNR PIRSDSGPGY
RLSRRATVGT MAQMPEPVNR DKDEFVAVDE RGGQDDAVMG LPISTGNYVA YLAGQEGSGL
QQAGHRNRGY SNLAQEKEAR EPRVSDPYLS SSQRGQLSSD FHAASSNNNQ KDNIRSSCFD
NRRASSAAVV PHAGWVFIQR GAFRSWKRYY AVLSGTEFKY SKGVGQSPKG YGLLMSVQRM
EDLRFGLQLE FGDGGTLQIR CLSDHDHEQW LRSMEKAIER NQNLNSRSKT SYTLTAAEQH
EGYLFKQEKN KAWKRCFFVV RIDGYIECRD GKHGTPDRKC SGYIKAVSFA DCHANGLAIQ
LSTDMCMVCY ADSYDDQMLW YGAISAAASA NGKIVQLTAS VKSCYVQTAL SNHAGWLYKQ
AGIFKGWKRL YFTLHGVELA YAKDTNSEIV LSDKAHMVEE WEGHANGLLI RLMSGRVWKV
HAETYETAKR WRSVISSACR HAETFNLKKY LNSRRRKKLR PVFGGWLTEV KKGSRLRRFY
VMDGSSLGVA NDVDNQLERL GTVVDVGSTR DLECGMVFTL ANGNKVKVNC DSLADSRCWY
ECLNFSLK
//
