ID A0A3M6VM43_9STRA Unreviewed; 375 AA.
AC A0A3M6VM43;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Actin {ECO:0008006|Google:ProtNLM};
GN ORFNames=DD237_001984 {ECO:0000313|EMBL:RQM17546.1}, DD237_001989
GN {ECO:0000313|EMBL:RQM17539.1}, DD238_001306
GN {ECO:0000313|EMBL:RMX67487.1};
OS Peronospora effusa.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Peronospora.
OX NCBI_TaxID=542832 {ECO:0000313|EMBL:RMX67487.1, ECO:0000313|Proteomes:UP000282087};
RN [1] {ECO:0000313|Proteomes:UP000282087, ECO:0000313|Proteomes:UP000286097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R13 {ECO:0000313|EMBL:RQM17539.1,
RC ECO:0000313|Proteomes:UP000286097}, and R14
RC {ECO:0000313|EMBL:RMX67487.1, ECO:0000313|Proteomes:UP000282087};
RA Fletcher K., Klosterman S.J., Derevnina L., Martin F., Koike S.,
RA Reyes Chin-Wo S., Mou B., Michelmore R.;
RT "Comparative genomics of downy mildews reveals potential adaptations to
RT biotrophy.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001836};
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the actin family.
CC {ECO:0000256|ARBA:ARBA00006752, ECO:0000256|RuleBase:RU000487}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMX67487.1}.
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DR EMBL; QLLG01000165; RMX67487.1; -; Genomic_DNA.
DR EMBL; QKXF01000094; RQM17539.1; -; Genomic_DNA.
DR EMBL; QKXF01000094; RQM17546.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M6VM43; -.
DR STRING; 542832.A0A3M6VM43; -.
DR VEuPathDB; FungiDB:DD237_001984; -.
DR VEuPathDB; FungiDB:DD237_001989; -.
DR Proteomes; UP000282087; Unassembled WGS sequence.
DR Proteomes; UP000286097; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR020902; Actin/actin-like_CS.
DR InterPro; IPR004001; Actin_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; ACTIN; 1.
DR PANTHER; PTHR11937:SF387; ACTIN; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00406; ACTINS_1; 1.
DR PROSITE; PS00432; ACTINS_2; 1.
DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840};
KW Reference proteome {ECO:0000313|Proteomes:UP000282087}.
SQ SEQUENCE 375 AA; 41898 MW; 50A4DD341E43B499 CRC64;
MEEEVQAVVI DNGSGMCKAG FAGDDAPRAV FPSIVGMPKH LGIMVGMNQK EAYIGDEAQA
KRGVLTLRYP IEHGIVTNWD DMEKIWSHTF YNELRVSPEE HPVLLTEAPL NPKANRERMT
QIMFETFSVP AMYVNIQAVL SLYASGRTTG CVLDSGDGVS HTVPIYEGYA LPHAIIRLDM
AGRDLTDYMM KILTERGYSF TTTAEREIVR DIKEKLTYVA MDFDGEMQKA TKSSALDKTY
ELPDGNVIVI GSERFRTPEV LFNPSMIGRE CSGIHGCTFQ TIMKCDVDIR RDLYNNVVLS
GGSTMFPGIG DRMMKEMTKL APTAMKVKII TPPERKYSVW IGGSILASLA TFQHMWISKT
EYDESGPSVV HRKCF
//
