ID A0A3M6VSL7_9STRA Unreviewed; 616 AA.
AC A0A3M6VSL7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=NOT2/NOT3/NOT5 C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DD238_002418 {ECO:0000313|EMBL:RMX69123.1};
OS Peronospora effusa.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Peronospora.
OX NCBI_TaxID=542832 {ECO:0000313|EMBL:RMX69123.1, ECO:0000313|Proteomes:UP000282087};
RN [1] {ECO:0000313|EMBL:RMX69123.1, ECO:0000313|Proteomes:UP000282087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R14 {ECO:0000313|EMBL:RMX69123.1,
RC ECO:0000313|Proteomes:UP000282087};
RA Fletcher K., Klosterman S.J., Derevnina L., Martin F., Koike S.,
RA Reyes Chin-Wo S., Mou B., Michelmore R.;
RT "Comparative genomics of downy mildews reveals potential adaptations to
RT biotrophy.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR005290}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR005290}.
CC -!- SIMILARITY: Belongs to the CNOT2/3/5 family.
CC {ECO:0000256|ARBA:ARBA00007682, ECO:0000256|PIRNR:PIRNR005290}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMX69123.1}.
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DR EMBL; QLLG01000036; RMX69123.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M6VSL7; -.
DR STRING; 542832.A0A3M6VSL7; -.
DR Proteomes; UP000282087; Unassembled WGS sequence.
DR GO; GO:0030015; C:CCR4-NOT core complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-UniRule.
DR GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.30.30.1020; CCR4-NOT complex subunit 2/3/5, C-terminal domain; 1.
DR InterPro; IPR038635; CCR4-NOT_su2/3/5_C_sf.
DR InterPro; IPR012270; CCR4-NOT_su3/5.
DR InterPro; IPR040168; Not2/3/5.
DR InterPro; IPR007282; NOT2/3/5_C.
DR InterPro; IPR007207; Not_N.
DR PANTHER; PTHR23326; CCR4 NOT-RELATED; 1.
DR PANTHER; PTHR23326:SF1; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3; 1.
DR Pfam; PF04153; NOT2_3_5_C; 1.
DR Pfam; PF04065; Not3; 1.
DR PIRSF; PIRSF005290; NOT_su_3_5; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR005290};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005290};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000282087};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|PIRNR:PIRNR005290};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR005290};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR005290}.
FT DOMAIN 4..231
FT /note="CCR4-Not complex component Not N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04065"
FT DOMAIN 486..611
FT /note="NOT2/NOT3/NOT5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04153"
FT REGION 270..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 34..61
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 132..159
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 270..356
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..431
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 68697 MW; CEC25D3DC3A9E9B2 CRC64;
MAGQRKLLSE IDRTLKKVSE GVDVFNEIWD KVYAATAQNQ KEKHEADLKK EIKKLQRFRD
QIKTWISNSD VKDKRPLVET RKLIEQKMEE FKVCEKETKT KAYSKEGLAQ VERLDPEQQA
RQESHAWIRD CLNQFNVQIE ALESDLERLQ SVKGRNRNKT EILEKEKLLS RHKWHILKLE
QINRLLDNSA LEPEQVDELK EDVEYYLEAN QEADFMETYG DDDIYEMLDL DTLGAAAQVA
LPTEQDVGIE DASSTTLVSS STAATIAVVS PTPTASTGRG KTPRKSASSS VITGIGRASS
VKPSDLKMST PSRSSSVTKS DSSPCNSLKT EIGKGRTTPL RTKSGSSSSE KGLSKAPTPV
PSSPAIGEQR TPARKVTPPT PQRSPSPSIG RGQFGSSSSA SPAAVRPPSG PAPSPPHSNS
SLPPPVPVPS PTAAVHAVGT VSAPSSGSGF GASTEALAVK SQPMEESPQL TDEQKQVLRL
IDESFNFTPE SRDSKKANRY VPRNLYPTPA SFPTTPSTLF SSAPIFEKLD VDTLFFIFYY
QQGSYQQYLA ARELKRRTWG YHKKYKTWFK RHEEPQVTGE DYEQGTFVYF DYETGWCQRI
KTEFTFEYSF LEDELQ
//
