ID A0A3M6XEA6_HORWE Unreviewed; 99 AA.
AC A0A3M6XEA6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Small nuclear ribonucleoprotein E {ECO:0000256|RuleBase:RU365053};
DE Short=snRNP-E {ECO:0000256|RuleBase:RU365053};
DE AltName: Full=Sm protein E {ECO:0000256|RuleBase:RU365053};
GN ORFNames=D0866_04714 {ECO:0000313|EMBL:RMY35274.1}, D0867_01626
GN {ECO:0000313|EMBL:RMY24073.1}, D0868_00495
GN {ECO:0000313|EMBL:RMY16122.1}, D0869_01178
GN {ECO:0000313|EMBL:RMX89041.1};
OS Hortaea werneckii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Hortaea.
OX NCBI_TaxID=91943 {ECO:0000313|EMBL:RMX89041.1, ECO:0000313|Proteomes:UP000281245};
RN [1] {ECO:0000313|Proteomes:UP000271337, ECO:0000313|Proteomes:UP000276864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EXF-6651 {ECO:0000313|EMBL:RMY35274.1,
RC ECO:0000313|Proteomes:UP000276864}, EXF-6654
RC {ECO:0000313|EMBL:RMY16122.1, ECO:0000313|Proteomes:UP000282582},
RC EXF-6656 {ECO:0000313|EMBL:RMX89041.1,
RC ECO:0000313|Proteomes:UP000281245}, and EXF-6669
RC {ECO:0000313|EMBL:RMY24073.1, ECO:0000313|Proteomes:UP000271337};
RX PubMed=29764372; DOI=10.1186/s12864-018-4751-5;
RA Gostincar C., Stajich J.E., Zupancic J., Zalar P., Gunde-Cimerman N.;
RT "Genomic evidence for intraspecific hybridization in a clonal and extremely
RT halotolerant yeast.";
RL BMC Genomics 19:364-364(2018).
CC -!- FUNCTION: Involved in pre-mRNA splicing. Binds and is required for the
CC stability of snRNA U1, U2, U4 and U5 which contain a highly conserved
CC structural motif called the Sm binding site. Involved in cap
CC modification. {ECO:0000256|RuleBase:RU365053}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU365053}.
CC -!- SIMILARITY: Belongs to the snRNP Sm proteins family.
CC {ECO:0000256|ARBA:ARBA00006850, ECO:0000256|RuleBase:RU365053}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMX89041.1}.
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DR EMBL; QWIJ01000044; RMX89041.1; -; Genomic_DNA.
DR EMBL; QWIK01000017; RMY16122.1; -; Genomic_DNA.
DR EMBL; QWIL01000099; RMY24073.1; -; Genomic_DNA.
DR EMBL; QWIM01000387; RMY35274.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M6XEA6; -.
DR VEuPathDB; FungiDB:BTJ68_09594; -.
DR Proteomes; UP000271337; Unassembled WGS sequence.
DR Proteomes; UP000276864; Unassembled WGS sequence.
DR Proteomes; UP000281245; Unassembled WGS sequence.
DR Proteomes; UP000282582; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0005685; C:U1 snRNP; IEA:UniProtKB-UniRule.
DR GO; GO:0005686; C:U2 snRNP; IEA:UniProtKB-UniRule.
DR GO; GO:0005687; C:U4 snRNP; IEA:UniProtKB-UniRule.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005682; C:U5 snRNP; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000387; P:spliceosomal snRNP assembly; IEA:UniProtKB-UniRule.
DR CDD; cd01718; Sm_E; 1.
DR Gene3D; 2.30.30.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR047575; Sm.
DR InterPro; IPR001163; Sm_dom_euk/arc.
DR InterPro; IPR027078; snRNP-E.
DR PANTHER; PTHR11193; SMALL NUCLEAR RIBONUCLEOPROTEIN E; 1.
DR PANTHER; PTHR11193:SF0; SMALL NUCLEAR RIBONUCLEOPROTEIN E; 1.
DR Pfam; PF01423; LSM; 1.
DR SMART; SM00651; Sm; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS52002; SM; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|RuleBase:RU365053};
KW mRNA splicing {ECO:0000256|RuleBase:RU365053};
KW Nucleus {ECO:0000256|RuleBase:RU365053};
KW Reference proteome {ECO:0000313|Proteomes:UP000276864};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU365053};
KW RNA-binding {ECO:0000256|RuleBase:RU365053};
KW Spliceosome {ECO:0000256|RuleBase:RU365053}.
FT DOMAIN 19..99
FT /note="Sm"
FT /evidence="ECO:0000259|PROSITE:PS52002"
SQ SEQUENCE 99 AA; 10947 MW; D801ACF82DC431DD CRC64;
MSGRAGGGGG GRKVLLPPIN FIFKLLQQHS TVQIWLYEQL GIRIEGKIRG FDEFMNLVID
DAVEVKQPTK AEPEPTDARR DLGQILLKGD NVCLIQSLS
//
