ID A0A3M7BP98_HORWE Unreviewed; 1099 AA.
AC A0A3M7BP98;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Replication factor C subunit 1 {ECO:0000256|ARBA:ARBA00020401, ECO:0000256|PIRNR:PIRNR036578};
GN ORFNames=D0866_00436 {ECO:0000313|EMBL:RMY41672.1}, D0868_07292
GN {ECO:0000313|EMBL:RMY03783.1};
OS Hortaea werneckii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Hortaea.
OX NCBI_TaxID=91943 {ECO:0000313|EMBL:RMY41672.1, ECO:0000313|Proteomes:UP000276864};
RN [1] {ECO:0000313|Proteomes:UP000276864, ECO:0000313|Proteomes:UP000282582}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EXF-6651 {ECO:0000313|EMBL:RMY41672.1,
RC ECO:0000313|Proteomes:UP000276864}, and EXF-6654
RC {ECO:0000313|EMBL:RMY03783.1, ECO:0000313|Proteomes:UP000282582};
RX PubMed=29764372; DOI=10.1186/s12864-018-4751-5;
RA Gostincar C., Stajich J.E., Zupancic J., Zalar P., Gunde-Cimerman N.;
RT "Genomic evidence for intraspecific hybridization in a clonal and extremely
RT halotolerant yeast.";
RL BMC Genomics 19:364-364(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036578}.
CC -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC {ECO:0000256|ARBA:ARBA00006116, ECO:0000256|PIRNR:PIRNR036578}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMY41672.1}.
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DR EMBL; QWIK01000591; RMY03783.1; -; Genomic_DNA.
DR EMBL; QWIM01000021; RMY41672.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M7BP98; -.
DR VEuPathDB; FungiDB:BTJ68_06643; -.
DR Proteomes; UP000276864; Unassembled WGS sequence.
DR Proteomes; UP000282582; Unassembled WGS sequence.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006271; P:DNA strand elongation involved in DNA replication; IEA:UniProt.
DR CDD; cd00009; AAA; 1.
DR CDD; cd17752; BRCT_RFC1; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012178; RFC1.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF6; REPLICATION FACTOR C SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08519; RFC1; 1.
DR PIRSF; PIRSF036578; RFC1; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR036578};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR036578};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR036578}; Nucleus {ECO:0000256|PIRNR:PIRNR036578};
KW Reference proteome {ECO:0000313|Proteomes:UP000276864}.
FT DOMAIN 339..418
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 424..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 997..1099
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..162
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..287
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1012..1034
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1099 AA; 120480 MW; A315FEEED146512C CRC64;
MPSDIRSFFG GKPAGTPAEK PKAKDEPKKG RGRPRKIVED DDEDEGVEEV KPKKASPKKR
AAPEPERVEE TTADDFFGAN GKPKRTEPAV KAAKKSGKEA ATTPVKKEGN GRANGSTRGS
ARKGKKVETY AEDEFPDDDL LDDTADNAKA DAAVGRRMGD DYEEATDEEE SKPLQPKKAQ
RSGKQKKLKD HDQDDYEPDG DVDMKDTNAD DDFVVPDGDE EIVEDRPAKK TPAKASKKRK
SPVVDDDDDD GLKVEEEPAK KSRASPAKKS SSAPKKPKQE PEQESAETRA IFDSIPTITA
PEPPKKDPNA EKPKFQYGGQ HANSAVPAGA IDYNDIPSGE ENCLAGLSFV FTGQLQRLGR
EQGQNLVKQY GGKVTGAPSK KTSYVVLGED AGPKKLETIK QHNLKIINEE GLFELIKRLP
ANGGDSAAAG KMAEKKKKEE EEMRKAAAEM EKEERARMAA AKPKPGAAPV SAKGNGKVTA
GKTGKQAEQG PDTRLWTVRY APTQLSQICG NKTQVEKLAR WLRAFPKNQR TGFKMPGADG
SGVHRAVMIH GPPGIGKTTA AHLVAKLEGY DIVESNASDT RSKKLVETGL KGVLSTTSLM
GYFGRGSDEV EASKKKLVLI MDEVDGMSAG DRGGVGALAA VCKKSHIPMI LICNDRKLPK
MRPFDYVTYD LAFRRPTTDM IRSRIMTIAY REGMKIPANV VNALIEGSGA DIRQVVNMIS
TAKLDSQGSG EGMSYEEGKD MSKAWEKHIV LKPWDMVSKI LGGGLFNPAS KSSLNDKQEL
YFNDHEFAPL MLQENYLNTN PQRTNQWNDN AKMKKLAQLD LVSKAADSIS DGDLVDRMIH
GSQQQWGLMP AHAMFSFVRP ASFVYGSMAG HQTRFTAWLG KNSSQGKLMR MVKEIQGHMR
LRVTADRHEI RQSYVPVLFE MLVKRLQTEG KESVPEIIEL MDQYFLTKED WEAIMELGVG
EADMERIKIE TQAKATFTRM YNNQSHPLPF MKASQVMAPK RAPAKEKPDL EEALEESEEE
APDPAEEAPE DDEGEVDLSK DKYVKQPKKK KAPAKTAAGG AKKGAAGKKG KAAAKDEEED
ESEEDAKPKK GKGKAKAKK
//
