ID A0A3M7L7Q2_9FLAO Unreviewed; 2951 AA.
AC A0A3M7L7Q2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Amino acid adenylation domain-containing protein {ECO:0000313|EMBL:RMZ58783.1};
GN ORFNames=D1632_14455 {ECO:0000313|EMBL:RMZ58783.1};
OS Chryseobacterium nematophagum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=2305228 {ECO:0000313|EMBL:RMZ58783.1, ECO:0000313|Proteomes:UP000267524};
RN [1] {ECO:0000313|EMBL:RMZ58783.1, ECO:0000313|Proteomes:UP000267524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JUb275 {ECO:0000313|EMBL:RMZ58783.1,
RC ECO:0000313|Proteomes:UP000267524};
RA Page A., Roberts M., Felix M.-A., Weir W.;
RT "Chryseobacterium nematophagum: a novel matrix digesting pathogen of
RT nematodes.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMZ58783.1}.
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DR EMBL; QWIV01000014; RMZ58783.1; -; Genomic_DNA.
DR Proteomes; UP000267524; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 3.
DR CDD; cd19531; LCL_NRPS-like; 2.
DR Gene3D; 3.30.300.30; -; 3.
DR Gene3D; 3.40.50.980; -; 6.
DR Gene3D; 1.10.1200.10; ACP-like; 3.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 3.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 3.
DR Pfam; PF13193; AMP-binding_C; 3.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 3.
DR SMART; SM00823; PKS_PP; 3.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 3.
DR SUPFAM; SSF47336; ACP-like; 3.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 3.
DR PROSITE; PS50075; CARRIER; 3.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 3.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 728..803
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1792..1867
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2856..2931
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2951 AA; 338955 MW; 55AA959B8C7F2660 CRC64;
MNDTQILSNI FWHNRIASKE KATFSKGRNK SLKKEILKEN FEGFIKVAKN NSLSKFTIVS
SVFSFVINKY FENYQGIIKV YPSHLIDLEK YLLLEIENDA GSFKKLLQNT ATEVRQVFSH
KNYNSDNLNL EPFSNFSIQF GQKTEHLNDD ISLLCEEIEA NILFTVFYKE NYPDYVIESL
LKNVINILLD YESLLNKNRK DYSFVDKEEL HQLLIEFNDT KREYPSDKTI VQLFEEQVEK
IPDNVAVVFE DIELTYHEIN GKANQLANYI KEKYIVENGE VIAILLPKSV DLLVSLLAIE
KIGCVYLPID INYPKDRIDY ILEDSKAKIL LSEQNIAQTL DFNQPYISLK LNEIQFKSTA
NLNVTIKSND VAYLIYTSGS TGKPKGVLVE HHSNINMSLD QIKTFGITAE DKIIWFASIA
FDASISEIMM SIYSGAALYI PTEEEQKDKD KFISFLQKTK STVVTFPPSY LDLLSKENLK
FLKTIITAGE TANPIKAKEI VENGINYYNA YGPTEYSVCT SIFHLNSYET DTSIPIGKPI
SNTRVYILDE DLRVVPIGVS GKLYISGVGL SRGYLNKPEL TAEKFVENPF EVGTKMYDTG
DLARWLPDGN IEFLGRKDFQ VKIRGYRIEL GEIETNISQF SPSIRQVVAE AKEANGEKVL
VAYYTKYDET NLDKRELREY LQSKLPEYMV PGFFVELETI PLTRNGKIDR KALPSVTGED
LIRREYVAPM NTTEEKLAEI WQEVLGVERV GITDNFFELG GHSLMVAQVL NRIHQSLSMH
LSFKDFFASP IIEGIAKRLR GKDYTSIPKA PEQESYPLTP SQQRLWVLSQ LEGGSQAYNM
PAVVTLRGEL NEEYFEKAFQ YLIDRHEILR TSFRSDNATG EIRQYITPKE GVHFTIELFD
FTGRNESEVE DYLQTANNDA FHLEESSLLR ATLLKRENEE HLFFLSMHHI IGDGWSTEVL
VSEVVEIYNN LLNGNTNEDE ILKEELAIQY KDYAVWLEEE IKGEKYQKAE SYWLDQFEGE
LAVLELPSYK TRPLIQTYNG DTISHLFSKE FTDKLKQYSE HHGVTLFMTL MAGIKALLYR
YTGQQDIIVG TPIAGREHPD LENQIGLYLN TLAIRTKLEE HNTFESILSK EKETLLSAYE
HQLYPFDELV GKLNIKRDPS RSALFDVLVV FQNQSQLQIG NKQNNIEGLQ LEGYDYPRKT
SQFDVSYSFA EEDGSLGLTI DYNTDIYDEF LIERMFGHFE NLLTQAIEDR KDTEGITAIE
TIDFLTEQER DQLLHEFNDT KVDYPRDKTI VQLFEEQVDK TPDNVAVVFE DTELTYRELN
EQANHLGDYL RQNYKIEPDD LVGIKLERSE KMIVAILGIL KSGAAYVPID PDYPAERIEY
IEQDTQAKVT VDATFLESYQ EELKKEEIQY TKQNLPIISR PDSLAYVIYT SGTTGQPKGV
MIENKGLINR LVWMQKAYSL SSEDVLLQKT TYSFDVSVWE LLWWSIYGAK LSVLTPKHEK
SPFDIIESIN KKRVTVIHFV PSMLMVFLNY LNSNKEHIEK INSLKQVFVS GEALTIPQKK
LFYEILPEIS LMNLYGPTEA SIDVSYYDCS NLIKGMSIPI GKPIDNISLY ILDSNLKSKE
LGSFGKLYIS GVGLSRGYLN KPELTAEKFV ENPFEVGTKM YDTGDLARWL PDGNIEFLGR
KDFQVKIRGY RIELGEIETN ISQFSPSIRQ VVAEAKEANG EKVLVAYYTK YDETNLDKRE
LREYLQSKLP EYMVPGFFVE LETIPLTRNG KIDRKALPSV TGEDLIRREY VAPMNTTEEK
LAEIWQEVLG VERVGITDNF FELGGHSLMV AQVLNRIHQS LSMHLSFKDF FASPIIEGIA
KRLRGKDYTS IPKAPEQESY PLTPSQQRLW VLSQLEGGSQ AYNMPAVVTL RGELNEEYFE
KAFQYLIDRH EILRTSFRSD NATGEIRQYI TPKEGVHFTI ELFDFTGRNE SEVEDYLQTA
NNDAFHLEES SLLRATLLKR ENEEHLFFLS MHHIIGDGWS TEVLVSEVVE IYNNLLNGNT
NEDEILKEEL AIQYKDYAVW LEEEIKGEKY QKAESYWLDQ FEGELAVLEL PSYKTRPLIQ
TYNGDTISHL FSKEFTDKLK QYSEHHGVTL FMTLMAGIKA LLYRYTGQQD IIVGTPIAGR
EHPDLENQIG LYLNTLAIRT KLEEHNTFES ILSKEKETLL SAYEHQLYPF DELVGKLNIK
RDPSRSALFD VLVVFQNQSQ LQIGNKQNNI EGLQLEGYDY PRKTSQFDVS YSFAEEDGSL
GLTIDYNTDI YDEFLIERMF GHFENLLTQA IEDRKDTEGI TAIETIDFLT EQERDQLLHE
FNDTKVDYPR DKTIVQLFEE QVDKTPDNVA VVFEDTELTY RELNEQANHL GDYLRQNYKI
EPDDLVGIKL ERSEKMIVAI LGILKSGAAY VPIDPDYPAE RIEYIEQDTQ AKVTVDATFL
ESYQEELKKE EIQYTKQNLP IISRPDSLAY VIYTSGTTGQ PKGVMIENKG LINRLVWMQK
AYSLSSEDVL LQKTTYSFDV SVWELLWWSI YGAKLSVLTP KHEKSPFDII ESINKKRVTV
IHFVPSMLMV FLNYLNSNKE HIEKINSLKQ VFVSGEALTI PQKKLFYEIL PEISLMNLYG
PTEASIDVSY YDCSNLIKGM SIPIGKPIDN ISLYILDSNL KSKELGSFGK LYISGVGLSR
GYLNKPELTA EKFIANPFEA GTKMYDTGDL ARWLPDGNIE FLGRKDFQVK IRGYRIELGE
IETNISQFSP SIRQVVAEAK DVNGEKVLVA YYTKYDETNL DKCELREYLQ SKLPEYMVPG
FFVELETIPL TRNGKIDRKA LPSVTGEDLI RREYVAPMNT TEEKLAEIWQ EVLGVEKVGI
TDNFFELGGH SLMAIKVINS INQIFKIDVN VSQLFEQNTI KQLAILINNI ILINNISTNQ
HEESDSEKFT I
//
