ID A0A3M7L9G8_9FLAO Unreviewed; 910 AA.
AC A0A3M7L9G8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Insulinase family protein {ECO:0000313|EMBL:RMZ58172.1};
GN ORFNames=D1632_17965 {ECO:0000313|EMBL:RMZ58172.1};
OS Chryseobacterium nematophagum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=2305228 {ECO:0000313|EMBL:RMZ58172.1, ECO:0000313|Proteomes:UP000267524};
RN [1] {ECO:0000313|EMBL:RMZ58172.1, ECO:0000313|Proteomes:UP000267524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JUb275 {ECO:0000313|EMBL:RMZ58172.1,
RC ECO:0000313|Proteomes:UP000267524};
RA Page A., Roberts M., Felix M.-A., Weir W.;
RT "Chryseobacterium nematophagum: a novel matrix digesting pathogen of
RT nematodes.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMZ58172.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QWIV01000015; RMZ58172.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M7L9G8; -.
DR Proteomes; UP000267524; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR PANTHER; PTHR11851:SF229; PEPTIDASE M16 DOMAIN PROTEIN; 1.
DR Pfam; PF00675; Peptidase_M16; 2.
DR Pfam; PF05193; Peptidase_M16_C; 2.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
FT DOMAIN 47..193
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 203..378
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
FT DOMAIN 521..621
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 658..839
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 910 AA; 102381 MW; 4088D99252009146 CRC64;
MKNLLFGMAV LFFTGAANPI FSQKTESPTF VGNIEGVKEY SLSNGMRVLL LSDQSQSNMV
VNIVYNVGSK DEGYGEKGMA HLLEHMLFKS TKNMGDIKKQ LSDKGGQANG TTWFDRTNYF
EIFPSNDENL KWSLQMEADR MINATILQSD LDKEFSVVRN EFEIGENDPT RVMMQNVFSS
GYTWHNYGNS TIGSKEDIER VKAPTLRKFY EKYYQPDNAT LIVAGKFDEK NALQYISEYF
SAIPKPSREL GGTYTVEPAQ NGEKYFEIKR NNDQQIVAAG YHTSAFADKD YAALAALYEI
LTSDPSGYLY KSLVETQKIS SVWTFSPVVR DPGMVYFNFD VPKDKDLNQA TNFVKAELDK
VGNTKYTADD LKRAKAKLIK DIENEKNNTI NFAINLTEIV GAGNYKLGFL YRDNVEKLTL
EDINRVAQKY FKTNNRTLGV FRPSSNEERV FPAEFRENQI ADLVKGYKGK ALEKEPAPFE
ASIANLKKNL TEGKLSNGMK YGLINKELKG EKVQGSFRFR IGNEKDLQDK NAVASITAAL
LKAGTKSKTK EQIQDELDQM KSSINLYAYG QNFILNISTY KQYYPKVMGI LQDILTNSIF
PETELSKTVI ETNTWLEGQL KDPNAIANNE VQRLSSPYPK TSIFYISSLQ EQIDDNKKVT
RAQIMNFYQN IMGASNGVGT IIGNLDPKLV AAELEKTFGK FTAKSKFVEV KPTFFETKKQ
DKNIITPDKE NAVALGTSSF RMAQDHPDYP ALVMANEILG SGGFLSARLP MRLREKDGIS
YGVGSYLSVP ITNDVASWNY YAYLNPTKRD AVEAAIKEEV GKALASGFTQ EELDSNKKSY
ANERKTNLGM ENTLINLVNT QLLFGVPVEK FDEQNAKIQN LKLTEVNDAL KKYLSENNII
SVFAGDFNKK
//
