ID   A0A3M7PBZ0_BRAPC        Unreviewed;       480 AA.
AC   A0A3M7PBZ0;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Acid-sensing ion channel 5 {ECO:0000313|EMBL:RMZ96523.1};
GN   ORFNames=BpHYR1_008769 {ECO:0000313|EMBL:RMZ96523.1};
OS   Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC   Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC   Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX   NCBI_TaxID=10195 {ECO:0000313|EMBL:RMZ96523.1, ECO:0000313|Proteomes:UP000276133};
RN   [1] {ECO:0000313|EMBL:RMZ96523.1, ECO:0000313|Proteomes:UP000276133}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HYR1 {ECO:0000313|EMBL:RMZ96523.1};
RX   PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA   Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA   Gomez A.;
RT   "Genomic signatures of local adaptation to the degree of environmental
RT   predictability in rotifers.";
RL   Sci. Rep. 8:16051-16051(2018).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|RuleBase:RU000679}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMZ96523.1}.
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DR   EMBL; REGN01012117; RMZ96523.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M7PBZ0; -.
DR   Proteomes; UP000276133; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000276133};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        34..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        443..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   480 AA;  55669 MW;  BEEF875DE74C8134 CRC64;
     MQKSKISNIK QIILENVETS TSHGIPNIFR SRNIILKILW TISVMGSFGY CVYCLSRNFR
     DFFEFKTNTQ IKYERVNQIQ FPAITFCNQY PFNINSNSYL IPIMKLGFSQ MTSWVFQPDN
     ILNYSNLMED AKYFLQNQTI VFKNELESIA FTIDFLLISC RFNQNECFKS DFETFFSPKY
     GFCYKFNGNQ SRGIRNIGMT GKKNGLSLEL YVGEPTIEYD IGKTSGIELF IHNWSSIPVA
     EAEGISLPGG LETNIAINQF FMKKQPRPYS NCIEDKYSQN SFSSHFYLET VRLYKQYEQK
     GCLNLCYHKN IKKKCGCYDP DFFFAESNLF CSFEEFTSCI LEYRKSMADS LENLACFEQC
     PEECDSVKYV YQTSQSNFPS PFYKKILMEF DKALNESKRG YVFENLDKYV LAVNIYYDEI
     ATTTIEETPA KTIEQLVAEI GGFLGLCIGI SFLTLIEIFD AIIKILLLFF SKSKINNESK
//