ID A0A3M7PD59_BRAPC Unreviewed; 402 AA.
AC A0A3M7PD59;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 08-NOV-2023, entry version 19.
DE SubName: Full=Phosphatidylinositol 3-4-5-trisphosphate 3-phosphatase TPTE2-like {ECO:0000313|EMBL:RMZ96992.1};
DE EC=3.1.3.16 {ECO:0000313|EMBL:RMZ96992.1};
DE EC=3.1.3.41 {ECO:0000313|EMBL:RMZ96992.1};
DE EC=3.1.3.48 {ECO:0000313|EMBL:RMZ96992.1};
GN ORFNames=BpHYR1_003622 {ECO:0000313|EMBL:RMZ96992.1};
OS Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=10195 {ECO:0000313|EMBL:RMZ96992.1, ECO:0000313|Proteomes:UP000276133};
RN [1] {ECO:0000313|EMBL:RMZ96992.1, ECO:0000313|Proteomes:UP000276133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYR1 {ECO:0000313|EMBL:RMZ96992.1};
RX PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA Gomez A.;
RT "Genomic signatures of local adaptation to the degree of environmental
RT predictability in rotifers.";
RL Sci. Rep. 8:16051-16051(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMZ96992.1}.
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DR EMBL; REGN01011706; RMZ96992.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M7PD59; -.
DR STRING; 10195.A0A3M7PD59; -.
DR Proteomes; UP000276133; Unassembled WGS sequence.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd14510; PTP_VSP_TPTE; 1.
DR Gene3D; 2.60.40.1110; -; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR045102; PTP_VSP_TPTE.
DR InterPro; IPR014020; Tensin_C2-dom.
DR InterPro; IPR029023; Tensin_phosphatase.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR12305; PHOSPHATASE WITH HOMOLOGY TO TENSIN; 1.
DR PANTHER; PTHR12305:SF60; PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE TPTE2-RELATED; 1.
DR Pfam; PF10409; PTEN_C2; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR SMART; SM01326; PTEN_C2; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS51182; C2_TENSIN; 1.
DR PROSITE; PS51181; PPASE_TENSIN; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:RMZ96992.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000276133}.
FT DOMAIN 79..255
FT /note="Phosphatase tensin-type"
FT /evidence="ECO:0000259|PROSITE:PS51181"
FT DOMAIN 164..224
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT DOMAIN 262..400
FT /note="C2 tensin-type"
FT /evidence="ECO:0000259|PROSITE:PS51182"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..26
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 402 AA; 46442 MW; 3E78310AD818CD61 CRC64;
MQSNSFNVDI EIENDEKSDN GTTESVDEGK EIHGVFILGR IIVIGRIIRL VLLIRSVRLI
LLTDGFQKSM RLTVGGNKRR YQKDGYDLDL CYISKRVIAM SFPSSGIDGV YRNRIEQVAK
FLDEKHPNKY KVYNLCSERT YDTSYFHERC ERVMIDDHNV PSLKDAIRFS KDVRNWMNAD
PENVIAVHCK GGKGRTGTMI CIWLLESKQY ANASEALYKF GDRRTNWDKG KIFQGVETPS
QSRFVGYYDI ICNKLNGLLP PIKYLRLTKV LIHSIRGIGN SDGSDFSMII YNNLKQVAAT
CNFGTNNNCQ YQFDSDNNRV VIESINSEIL SEEVKVMFFS SNKNVPKYYD DCAFFFSFHA
SFIESDRLFI PRNDLDNPHK EKFWDVYNEN FAVEVLFETV DQ
//
