ID A0A3M7Q332_BRAPC Unreviewed; 450 AA.
AC A0A3M7Q332;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 28-JUN-2023, entry version 14.
DE SubName: Full=26S proteasome non-ATPase regulatory subunit 12 {ECO:0000313|EMBL:RNA05856.1};
GN ORFNames=BpHYR1_033555 {ECO:0000313|EMBL:RNA05856.1};
OS Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=10195 {ECO:0000313|EMBL:RNA05856.1, ECO:0000313|Proteomes:UP000276133};
RN [1] {ECO:0000313|EMBL:RNA05856.1, ECO:0000313|Proteomes:UP000276133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYR1 {ECO:0000313|EMBL:RNA05856.1};
RX PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA Gomez A.;
RT "Genomic signatures of local adaptation to the degree of environmental
RT predictability in rotifers.";
RL Sci. Rep. 8:16051-16051(2018).
CC -!- SIMILARITY: Belongs to the proteasome subunit p55 family.
CC {ECO:0000256|ARBA:ARBA00006397}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNA05856.1}.
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DR EMBL; REGN01007567; RNA05856.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M7Q332; -.
DR STRING; 10195.A0A3M7Q332; -.
DR Proteomes; UP000276133; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR040134; PSMD12/CSN4.
DR InterPro; IPR040896; RPN5_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10855:SF1; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12; 1.
DR PANTHER; PTHR10855; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4; 1.
DR Pfam; PF01399; PCI; 1.
DR Pfam; PF18098; RPN5_C; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Proteasome {ECO:0000256|ARBA:ARBA00022942, ECO:0000313|EMBL:RNA05856.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000276133}.
FT DOMAIN 230..413
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
SQ SEQUENCE 450 AA; 52246 MW; C1C8D4B76D5BC860 CRC64;
MSLYGKLEKQ EADYSAVVEE KIPECQKMVN SGRLQEAIEI LLQLEKQARV AGDAHSTSRI
LTTIVRFCFE QRNFEALNEN IHLLTKRRSQ LKQAVTKMVQ EACTYVDQIS DMETKLKLID
SLRTVTAGKI YVEIERARLT RKLAEFKEAA GNIDEAASIL QELQVETFGS MEKREKIEFL
LEQMRVCLLK GDFIRTQIIS RKISIRSFED EKLHDLKLKF YELMIKLDQH DANYFAVCKH
YKQIYDTPRI KENSLMMKEA LKNIVIYLLL SPYGNEQQNL LHIISQDKNL QQLPKYNELV
KLIKTDEVIN WRSLIEHFEQ DLKVGDSNLP ATDAFKSEEG AKRWADFKTR IVEHNMRVMA
KYYTRISTKR MANLLDLTED ETEEFLSNLV TNKTVSGKID RLAGIVTFES QKDINEVLND
WSHNLSALMK SINNTTHLIN KEEMVHAAKA
//
