ID A0A3M7Q5H8_BRAPC Unreviewed; 340 AA.
AC A0A3M7Q5H8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Amiloride-sensitive sodium channel subunit delta {ECO:0000313|EMBL:RNA06509.1};
GN ORFNames=BpHYR1_054194 {ECO:0000313|EMBL:RNA06509.1};
OS Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=10195 {ECO:0000313|EMBL:RNA06509.1, ECO:0000313|Proteomes:UP000276133};
RN [1] {ECO:0000313|EMBL:RNA06509.1, ECO:0000313|Proteomes:UP000276133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYR1 {ECO:0000313|EMBL:RNA06509.1};
RX PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA Gomez A.;
RT "Genomic signatures of local adaptation to the degree of environmental
RT predictability in rotifers.";
RL Sci. Rep. 8:16051-16051(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC 1.A.6) family. {ECO:0000256|RuleBase:RU000679}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNA06509.1}.
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DR EMBL; REGN01007367; RNA06509.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M7Q5H8; -.
DR Proteomes; UP000276133; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR InterPro; IPR001873; ENaC.
DR PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR PANTHER; PTHR11690:SF248; DEGENERIN-LIKE PROTEIN UNC-105; 1.
DR Pfam; PF00858; ASC; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU000679, ECO:0000313|EMBL:RNA06509.1};
KW Ion transport {ECO:0000256|RuleBase:RU000679};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000276133};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW ECO:0000256|RuleBase:RU000679};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT TRANSMEM 32..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 340 AA; 39181 MW; 3C37B62CCF4EED45 CRC64;
MKSKSSFRDV FNKWIEASTA HGISNIFLNK NWFLKFFWIL CVLSSVGYCI FNLSRTLNDF
LDFNIGIHSI SDCIFLQKSE NSTNAKIFMK GLKKNALENL EKNKSLSDIL EEINFNLKRI
DTIRKHGFNI DEMLVNCQFN RFACTKNDFE YFMLAEFGNC YKFNSDTKTP GKKNGLRLEL
YTGTLDKDLD LVKSSGIHLF IHNHSTVIFS ESDSINLSNG FETDIVVSQQ HSYKLSKPHS
NCIKDPTSFN SFESDLYKKS IELYGIYQQK TCLIMCYHEY IKMQCGCYFS DALGVTFNSS
CNASLINCSK KAYENFQNSA KSLECFDLCP IECETIYFNI
//
