ID A0A3M7QFJ8_BRAPC Unreviewed; 1254 AA.
AC A0A3M7QFJ8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Putative global transcription activator SNF2L2 isoform X1 {ECO:0000313|EMBL:RNA10217.1};
DE EC=3.6.1.15 {ECO:0000313|EMBL:RNA10217.1};
DE EC=3.6.1.3 {ECO:0000313|EMBL:RNA10217.1};
DE Flags: Fragment;
GN ORFNames=BpHYR1_002745 {ECO:0000313|EMBL:RNA10217.1};
OS Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=10195 {ECO:0000313|EMBL:RNA10217.1, ECO:0000313|Proteomes:UP000276133};
RN [1] {ECO:0000313|EMBL:RNA10217.1, ECO:0000313|Proteomes:UP000276133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYR1 {ECO:0000313|EMBL:RNA10217.1};
RX PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA Gomez A.;
RT "Genomic signatures of local adaptation to the degree of environmental
RT predictability in rotifers.";
RL Sci. Rep. 8:16051-16051(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNA10217.1}.
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DR EMBL; REGN01006258; RNA10217.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M7QFJ8; -.
DR STRING; 10195.A0A3M7QFJ8; -.
DR Proteomes; UP000276133; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0042393; F:histone binding; IEA:InterPro.
DR GO; GO:0017111; F:ribonucleoside triphosphate phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd17996; DEXHc_SMARCA2_SMARCA4; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.40.5.120; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR006576; BRK_domain.
DR InterPro; IPR037259; BRK_sf.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014012; HSA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029295; SnAC.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR10799:SF973; ATP-DEPENDENT HELICASE BRM; 1.
DR PANTHER; PTHR10799; SNF2/RAD54 HELICASE FAMILY; 1.
DR Pfam; PF07533; BRK; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07529; HSA; 1.
DR Pfam; PF14619; SnAC; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00592; BRK; 1.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00573; HSA; 1.
DR SMART; SM01314; SnAC; 1.
DR SUPFAM; SSF160481; BRK domain-like; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51204; HSA; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:RNA10217.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000276133}.
FT DOMAIN 151..223
FT /note="HSA"
FT /evidence="ECO:0000259|PROSITE:PS51204"
FT DOMAIN 414..579
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 728..895
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1056..1126
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 333..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 972..1034
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1146..1254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..297
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1165..1195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1202..1220
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1221..1243
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RNA10217.1"
SQ SEQUENCE 1254 AA; 144699 MW; D99179E4034787F5 CRC64;
SKPQPAPAAL PQAGTARQMT PMTSRPSHNA IPMAAYKHMN KVAPCAKPVG LDPAQLLKER
ENFIVHKIKY RIGELERLPL KQLGDHLQTK VAIELKALRL LDFQKQLRHE IVSCMRADST
LETGLNAKAY KRCKRQTLRE ARITEKMERQ QKQEAERKRR QKHLEYLNAV IEHSKTFKEQ
HRANLAKVNK MAKGVINWHT NTERIQKKEQ ERLEKERIKL LMAEDEEGYR KLVNEKKDKR
LQYLLQQTDD YIESLTKLVR EHQDDLMKQK SSVKTKSSAK TTKTDTAHTD DAEDRRVKVA
NSMTGEVIEG GDAPRSSELD AWLEAHPDWH AVPRELDHDN DNDSVPDDDD DDEHQDKADT
SLTTAEDDEY NSASSKNSYY GVAHRLREKV TEQASILVGG TLKPYQVRGL EWLVSLYNNN
LNGILADEMG LGKTIQTISL ITYLMEKKKV NGPFLIIVPL STLSNWVNEF ARWAPSVISV
VYKGDPNQRK AISGLLKTGK FNVLVTTYEY IIKDKSILAK IKWKYMIIDE GHRMKNHHCK
LTQILNTFYI APHRLLLTGT PLQNKLPELW ALLNFLLPSI FKSCSSFEQW FNAPFNTSGE
KVELNNEETL LIIRRLHKVL RPFLLRRLKK EVESQLPDKV EYIIKCDMSA LQRVIYHSMK
TNGVMLTEDK NGKNTTKTLM NTIMQLRKIC NHPFIFQEIE EKLAQHLKYP GGIINGPEIY
RASGKFELLD RILPKLKQTG HRVLMFCQMT SLMTVMEDYF NYRNFRYLRL DGGTKAEERG
DLLKVFNEPG SEYFIFILST RAGGLGLNLQ VADTVIIFDS DWNPQQDLQA QDRAHRIGQK
NEVRVLRLMT VNSVEEKIVA AAKHKLNVDS KVIQAGMFDA KSTGQERRQY LQTILSQESN
EVDDDPEVPD DETVNQMIAR SEDEYELFQR MDIERRRVEA REQNRKPRLM EDSELPAWLI
KDDSQLEQMR LEAQGHIDES IYGRGTRVRK EEDEDGDDAE QGEDTAESPQ PQVKRKRGRP
AASTKKISKH DQKEAHRLHK KIKFLLDCLL NYADNDGRLL SEPFVQLPTR RELPDYYEII
KRPIDIKKIQ AKIKDNKYAS LDQLADDVEL MFRNAQEYNV ESSLIYEDSV VLLSVFKTAK
ARLMEREAAS ASEKEEESDD DGDENEDGKK SKRARLDESK RSKKSAKKTD EYEPMDDSVN
VAVGADDDEE EDDVDINFDF NDDEEAKIAT ERRNERKQQA GFRQIQDEIK TGND
//
