ID A0A3M7R7E8_BRAPC Unreviewed; 743 AA.
AC A0A3M7R7E8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Pleckstrin domain-containing 1-like {ECO:0000313|EMBL:RNA19460.1};
GN ORFNames=BpHYR1_016503 {ECO:0000313|EMBL:RNA19460.1};
OS Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=10195 {ECO:0000313|EMBL:RNA19460.1, ECO:0000313|Proteomes:UP000276133};
RN [1] {ECO:0000313|EMBL:RNA19460.1, ECO:0000313|Proteomes:UP000276133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYR1 {ECO:0000313|EMBL:RNA19460.1};
RX PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA Gomez A.;
RT "Genomic signatures of local adaptation to the degree of environmental
RT predictability in rotifers.";
RL Sci. Rep. 8:16051-16051(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNA19460.1}.
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DR EMBL; REGN01004039; RNA19460.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M7R7E8; -.
DR STRING; 10195.A0A3M7R7E8; -.
DR Proteomes; UP000276133; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13193; FERM_C_FARP1-like; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR041788; FARP1/FARP2/FRMD7_FERM_C.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45858; FERM DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45858:SF5; MOESIN_EZRIN_RADIXIN HOMOLOG 1; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000276133}.
FT DOMAIN 1..275
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 412..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 490..519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 719..743
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..429
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..468
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 490..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 729..743
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 743 AA; 83700 MW; C069C1CB98658C22 CRC64;
MLDDSEIPFQ IESKTTGNEL INLVYQYLKL VESDYFGLEF IDSKGKKNWL DYDKPVAKQI
QNNLKLIFCV KFYTPDPGQL EEEYTRYLYA LQIKRDLAEG LLLCTDATAS LLASYILQAE
IGDFNENFNP LTCFQNKNFF PHQNPEHESK IIDYYKNHIG QTPADADMNL LDIARKIELY
GILMHAARDH EGVQLNLAVA HMGILVFQNC TKINTFSWAK IRKLSFKRKK FLVKLHPENY
GFYKDTVEFY FDNRDGSKNF WKKCIEHHAF FRCISAQRMP RQKSRLLTRG SSFRYYGRTQ
KELIENAREN LAKNRSFDRS YHSMRNISHY NYSGSSGAIN FHPQGTQSLN RNLASRSTGA
ILQPGYATTG HGSTNFISST DSVNLYQHQD HNERTIHSRH SLGKEKTLAL SDHDHSDDQN
TDEDCDQHGN GPKNATSTFK PPSVSLPIQQ EKKDHMDRSN PNKIYSRKEV IQTTYKEEFL
HTTTTTNLYS ADKLSPSSSS PSSSSSNPNQ EAHEDDDEDV KKLCVTPVVL PSSQVKKADN
VRNKLNSDDY LSFSLSSSIS TSSISYINEL LDASDSSMDT SSISSTLSVI DLKTGAQFQT
NGIANTRPTV KTLPHTIKYA EVGKLPPKSS FSYRNDTINV GDNLERKLAR QKNSLVSPVS
SSSSCGQDES CSETYEDVID KCLDDESLSK IMALDGSEAN TPVDDGCSFG QSIAKSSDLL
IDSPPIEHSP KHVSSNTDSS SFE
//
