ID A0A3M7SF30_BRAPC Unreviewed; 1301 AA.
AC A0A3M7SF30;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Neurexin-4 isoform X2 {ECO:0000313|EMBL:RNA34413.1};
DE Flags: Fragment;
GN ORFNames=BpHYR1_000881 {ECO:0000313|EMBL:RNA34413.1};
OS Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=10195 {ECO:0000313|EMBL:RNA34413.1, ECO:0000313|Proteomes:UP000276133};
RN [1] {ECO:0000313|EMBL:RNA34413.1, ECO:0000313|Proteomes:UP000276133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYR1 {ECO:0000313|EMBL:RNA34413.1};
RX PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA Gomez A.;
RT "Genomic signatures of local adaptation to the degree of environmental
RT predictability in rotifers.";
RL Sci. Rep. 8:16051-16051(2018).
CC -!- SIMILARITY: Belongs to the neurexin family.
CC {ECO:0000256|ARBA:ARBA00010241}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNA34413.1}.
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DR EMBL; REGN01001483; RNA34413.1; -; Genomic_DNA.
DR STRING; 10195.A0A3M7SF30; -.
DR Proteomes; UP000276133; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00057; FA58C; 1.
DR CDD; cd00110; LamG; 4.
DR Gene3D; 2.60.120.1000; -; 1.
DR Gene3D; 2.60.120.200; -; 4.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF49; AXOTACTIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF02210; Laminin_G_2; 4.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00231; FA58C; 1.
DR SMART; SM00282; LamG; 4.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 4.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01285; FA58C_1; 1.
DR PROSITE; PS50022; FA58C_3; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 4.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000276133};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1231..1256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..154
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 158..347
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 352..539
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 541..578
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 799..967
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 968..1004
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1008..1195
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RNA34413.1"
SQ SEQUENCE 1301 AA; 147070 MW; 65E36B23DCC4183A CRC64;
WVNASFECTQ PIPLGSENGI LPDSSFTATS FSSSREPYRA RLNGQFAWRP RKMDSNEYLI
VNFESRVIIT SVATQGRRAA REFVTLYALQ YSDNGMNWFY YTDENKIIMN FPGNTDDNTV
RENRFHEPII AKYVRINPRQ WNNFIALRVE FYGCPYDPTT VTFNRAALAS YDAMFQPLNS
YQDELLLRFR TNDPSALIFY TKGTQNNDYM SIELRNGSLY VGVDLGSTVE KPGEMLIRCG
SLLDDFQWHD VKVRRTGRSI LVVVDQLVVR NESTSLFTSF NFDGKMYAGG APSHIDRGIS
IRSNFMGCLE NVIYRSFTEN RVIDILKGAR YQWPHYQVQG GYLSYSCVDL NQMPMTFKDR
QSYLYAQRNP GSQRLDVSFG MRTFELEGLL YHHRFAKDTA NQDTGYIKVY LNEGALLIKF
RLGAKQKPDQ TMTHRRAALN DGLWHDISLS ITIDMINVTV DFEPEIVRGT FKIQTGEMFY
IGGGVHDDLS VPNFVGCFRR LTLNDGRQVT PQNVRSLKDG PLASANDYVI SVGVLINSCE
ILDKCTPNPC QHGATCLQTW DNFRCDCSRT GYGGAVCHTS EHPLSCLDYK MTRMQQRVHA
YHADLPLTID VDGSGPIGPF QVTCKFGSQM ENMNVTQVDH YSHGEIVVKG YKAPGSYSSH
IVYTAAAVQL NELVQRSYAC SQYVKVKCKG ARFLNYPGEP FGWWVGRTNQ PMYYWGGSED
GIAKCRCGVN QECDVADVFC NCDSGDTENE RHDDGLLNNK LHLPVYKIFL GDTGDVNEDR
YIKYSIGSLV CEGDRLYDNT VTFRKQDALL HIDESESGRM AVDVRFQFRT SVTSGILVQK
VGNFSGDLIE VKLLTAREIA FRYSAGSGVQ LISIGTPFDL NDNEWHTVQL ERNRKEARMN
VDSISAGQPE DLNAYRPFMF TSNLTIGAAV SYRDGFVGCV RGLQLNGKLI DLAELARRAE
YGVSEGCVGK CASSPCLNNG TCVEQYSTFE CDCTFTPFRG PICGTEIGTI LEASNMIKYT
FPTEGVTATE EETISAQFAT YNKQGIIMQI LSDKKDEKGL VDYFTLEMNN NGGVRVRFNY
GFDNFEFNPP YDLSNGQNHE LIVVRRNRGQ SISIKVDEHL AYSFNFTRGS FIDMVFDSPR
YLYVGRNDTM RPDTGFIGCV SRLQFNRIFP LKYAFLEVAD ADLEVFGPEI REWQCAIDPV
TYAPEAVEIP PDRDIKIIQL PNVHAPPLQD WRYATLLGVG LAVLLATAFG FIIFFYHKYA
YKGSYVTKED KGAVHALDAD EAITKGDHRH PNIAEKKEWF L
//
