ID A0A3M7SH71_BRAPC Unreviewed; 483 AA.
AC A0A3M7SH71;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Aldehyde dehydrogenase family 8 member A1 {ECO:0000313|EMBL:RNA35112.1};
GN ORFNames=BpHYR1_053222 {ECO:0000313|EMBL:RNA35112.1};
OS Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=10195 {ECO:0000313|EMBL:RNA35112.1, ECO:0000313|Proteomes:UP000276133};
RN [1] {ECO:0000313|EMBL:RNA35112.1, ECO:0000313|Proteomes:UP000276133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYR1 {ECO:0000313|EMBL:RNA35112.1};
RX PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA Gomez A.;
RT "Genomic signatures of local adaptation to the degree of environmental
RT predictability in rotifers.";
RL Sci. Rep. 8:16051-16051(2018).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNA35112.1}.
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DR EMBL; REGN01001371; RNA35112.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M7SH71; -.
DR STRING; 10195.A0A3M7SH71; -.
DR Proteomes; UP000276133; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07093; ALDH_F8_HMSADH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR43720; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43720:SF2; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000276133}.
FT DOMAIN 16..478
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 249
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 483 AA; 53216 MW; BFEE0DFA2175290F CRC64;
MVIQITNFIN NVFMPTSNHI ESYDPSNGQL LCKVPDSGKN ECDMAIEAAA QAFKTWSMTS
QMERAKILNR IADEIEKNID ELAKAESQDQ GKPLSISTNF EIPRAAYNFR FFAAAILNHK
NESTELPHLK SFSYTTEVPS GVAVLISPWN LPLYLLTWKI APCIASGCTC VCKPSEFTSL
TAFLLCDILL KAGLPQGVVN IVFGLGSKIG NDLVTHPEAK LISFTGGTVT GNVIRKVTAN
EPAKRLSLEL GGKNPGIVFQ DADLNKHIKA IGNSCFQNSG QICLCSSRYY VHVSRINEFL
DLLVKHARGM VVGDPFDKNT NMGPVVSKQH YDKVMSYIDQ AAKLGCEILC GETVDEKPAG
LNSNGYYILP TVITNLEDSS PLMQEEIFGP VVCVTTFHEE DEVIERANNN RYGLAATLWT
NDVGRAHRVS RALLAGTTWI NCFLVRDLNM PFGGFKDSGA GREGYPYSFE FFTEKKTICV
NYA
//
