ID A0A3M7SK03_BRAPC Unreviewed; 843 AA.
AC A0A3M7SK03;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 22-FEB-2023, entry version 14.
DE SubName: Full=DNA-dependent kinase catalytic subunit {ECO:0000313|EMBL:RNA36049.1};
GN ORFNames=BpHYR1_052697 {ECO:0000313|EMBL:RNA36049.1};
OS Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=10195 {ECO:0000313|EMBL:RNA36049.1, ECO:0000313|Proteomes:UP000276133};
RN [1] {ECO:0000313|EMBL:RNA36049.1, ECO:0000313|Proteomes:UP000276133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYR1 {ECO:0000313|EMBL:RNA36049.1};
RX PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA Gomez A.;
RT "Genomic signatures of local adaptation to the degree of environmental
RT predictability in rotifers.";
RL Sci. Rep. 8:16051-16051(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNA36049.1}.
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DR EMBL; REGN01001246; RNA36049.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M7SK03; -.
DR STRING; 10195.A0A3M7SK03; -.
DR Proteomes; UP000276133; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR012582; DNAPKcs_CC3.
DR InterPro; IPR045581; DNAPKcs_CC5.
DR Pfam; PF08163; DNAPKcs_CC3; 1.
DR Pfam; PF19704; DNAPKcs_CC5; 1.
DR SMART; SM01344; NUC194; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:RNA36049.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000276133};
KW Transferase {ECO:0000313|EMBL:RNA36049.1}.
FT DOMAIN 10..390
FT /note="DNA-dependent protein kinase catalytic subunit CC3"
FT /evidence="ECO:0000259|SMART:SM01344"
SQ SEQUENCE 843 AA; 98534 MW; 6461310B31A4EC4A CRC64;
MYNNQFGFRK KIKNIGAIYN RLNVSIVVYA DDIILISMEQ NSLSSDLKSF IYKTYCLSKF
IYGLGCVKDG KELTKEVLRK SRKHMNEYVN FNTGQESAKI EANKDLERIL HCSAYNCLIS
LFIRTQTEPK LYLAFLFKDD PSKNEFVFEP LIDKIKSYNF CVEMENFTQR KTKFISIRDE
FKVIKADTNS RSANYISTMH STSSLSTQNL YSSSLSEELS VFDFSVHSSY NQAYNSQSSV
TRAPSFRRSY TDDELNSQEQ SVEIELDELN QHESMDNLIS LFQSLVVNKI TPIYDNGQLP
SEMPPWMTFV HKKILDVYTH ENIKLFLIRA IANTESIFKP YCKFWYSALI GFLVNSSLCR
DLAQMDCFTL DLMVMLLSWG SIQKPDQSEA KLINRLFTLL IKRCYHENRA VLKNNIELIK
TMTECWRDMI QVPVEVINNF LTSNDHRKLS TGIQLFGVVL SNGIENYEYP MDISRLDFFK
SLINCIKEPS KLIHAPAAEV VGMLLKRFDS HDKEYFENTV SHLFEILREA DTSLFITSIH
KIQLNYAAIS ERFMTKLVFF LPQLYGDFKK MCAESILSSI RVLQDPLFKS KNFIDMLTHR
DTPIQLICLK MIHETLDKQT DEDLDRLMPH LEKFIHHPHL SCRYQFVLIL ISLYEIYQFK
VNQIGSTSQI LNFSKENLLK ALIDEDTSIR VMAQNFWTEK ADMPSNTIDR MLLIVEKLYS
PKTEREFLSY STNLLLEKTS KSPDYNRLIY ENPLSECIFR EYNLSADWRR RHEIMTPLFA
ETVTNTFTES VDLRHNLRAT QQTLQFQPTL KNKKKKISHL KLIKLPQLRL KIAKKIAKKK
SKF
//
