ID A0A3M7SXN3_BRAPC Unreviewed; 544 AA.
AC A0A3M7SXN3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Rho guanine nucleotide exchange factor 17 {ECO:0000313|EMBL:RNA40340.1};
DE Flags: Fragment;
GN ORFNames=BpHYR1_042481 {ECO:0000313|EMBL:RNA40340.1};
OS Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=10195 {ECO:0000313|EMBL:RNA40340.1, ECO:0000313|Proteomes:UP000276133};
RN [1] {ECO:0000313|EMBL:RNA40340.1, ECO:0000313|Proteomes:UP000276133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYR1 {ECO:0000313|EMBL:RNA40340.1};
RX PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA Gomez A.;
RT "Genomic signatures of local adaptation to the degree of environmental
RT predictability in rotifers.";
RL Sci. Rep. 8:16051-16051(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNA40340.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; REGN01000651; RNA40340.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M7SXN3; -.
DR STRING; 10195.A0A3M7SXN3; -.
DR Proteomes; UP000276133; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR039919; ARHGEF10/ARHGEF17.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR12877; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR12877:SF15; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 17; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000276133}.
FT DOMAIN 210..395
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 51..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 544
FT /evidence="ECO:0000313|EMBL:RNA40340.1"
SQ SEQUENCE 544 AA; 62993 MW; 5007009900EDE590 CRC64;
MTSRWKFSTE TKRSVSINSS KPFGIISPKS KLSMLSSFPF RYPFASDGCT TSNTTTSTSP
QHNSPQSVSN ASSLVAEETN SSSLGGTYCS GFDSGSNDEI LFKKPDSCVE NPSNILKAID
DKKTNLFFVQ GDDDYDDNRR NMYEEKRDVF MDTFRHDKIN PLETVQSELT LFSTNTLPNR
YFDDSSGLKR YGVRRHHSAP QPDAKWLQAK RQAIVVQMYD TEKSYVEALK ILVNKYYLPL
KEKDIVDRNL INDIFYKIPE IHVHHELFLS WLKTKFDTWD SHQTIGDILF NIFAKQSVIE
TYISFVNNYR TSQEAIRISK EQSSIFCKFL EQQTRDHRGK LTLKDLIIQP VQRIPRYELY
IKDFLKCTPP NHPDHQYLIK AQTELHNLAE KIDQVHKEVN DSYGSDSLAV LQIIQDLVEN
LDDLVTAYRY YIRHDMLTIV SSSGMKKDRC LFLFSDLVIL TSCKRRSGNI NKKPNTIILN
SPIGKQYLEN SKHKLIMKFQ LEDIDLTNNI LTKKLSIEKD FLEEDLNMIN RINEIAKNIS
YPHQ
//
