ID   A0A3M7SYQ9_BRAPC        Unreviewed;       940 AA.
AC   A0A3M7SYQ9;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=MutS-like protein {ECO:0000313|EMBL:RNA40825.1};
GN   ORFNames=BpHYR1_006774 {ECO:0000313|EMBL:RNA40825.1};
OS   Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC   Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC   Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX   NCBI_TaxID=10195 {ECO:0000313|EMBL:RNA40825.1, ECO:0000313|Proteomes:UP000276133};
RN   [1] {ECO:0000313|EMBL:RNA40825.1, ECO:0000313|Proteomes:UP000276133}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HYR1 {ECO:0000313|EMBL:RNA40825.1};
RX   PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA   Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA   Gomez A.;
RT   "Genomic signatures of local adaptation to the degree of environmental
RT   predictability in rotifers.";
RL   Sci. Rep. 8:16051-16051(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RNA40825.1}.
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DR   EMBL; REGN01000587; RNA40825.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M7SYQ9; -.
DR   STRING; 10195.A0A3M7SYQ9; -.
DR   Proteomes; UP000276133; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0007127; P:meiosis I; IEA:UniProt.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   Gene3D; 1.10.1420.10; -; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR045076; MutS_family.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR   PANTHER; PTHR11361:SF20; MUTS PROTEIN HOMOLOG 5; 1.
DR   Pfam; PF05192; MutS_III; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR   SMART; SM00534; MUTSac; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000276133}.
FT   DOMAIN          306..635
FT                   /note="DNA mismatch repair protein MutS core"
FT                   /evidence="ECO:0000259|SMART:SM00533"
FT   DOMAIN          654..853
FT                   /note="DNA mismatch repair proteins mutS family"
FT                   /evidence="ECO:0000259|SMART:SM00534"
SQ   SEQUENCE   940 AA;  109665 MW;  E30E84268A7DEE92 CRC64;
     MFSKFNLIDS FQSNSELNEI PLIDNNESLN LSENLLHQVD STKLLTIDKQ VLEKFEENFS
     DDIDDNEIYL CLYYQSNKIA CSYYDLNKKC LFYSCEIQED SKFQLTETII DDLQPNCIIT
     SPRCDSKFLN FLKQKCKYDL KKLPNNTNLI PEDSLLTNDD QSYELMLKLR ENLIQFVLVP
     SGEFNFDACK ERIFKISTLE SLPERISEAE KIFYFSSLID FDSKLTIKSC GGLLKYLSTN
     RINFELERSI FETPIFKIKK IELKNMLLLD QNAFKSLQIF NDVDYVYAYK QTNFDTLAFR
     THLNDKFNNT LYSLFLSRIN TKFGIGKLRS FMLKPTRDLN ILHQRHKIIN FYLDPRNSEL
     AKLTIKHLKK CKYINPILKR MRLTRCGLND WKRLYRTTQS FLELCKMKRS LSLYLHSESI
     DSSFEVKFDF LVNLFERTID LKESNEKNEI RVSKNISKDL DTKRQMYSQL PEFLTEVAQR
     EMITYSLNGC KTTYLQLIGF LLIITREDLN LNNFSSNFCD RFAEFEQKNQ LKFVFKSNEK
     MYYKTPLCVE LDKNIGDLAT VINDLQSEIL DNLQTNFIKY SHLYAQMVDF CAEIDCLLSF
     ASVAKEFDYS KPEFDFTKES FVSAKSARHP LIELMFDSFS SFIPNDIHSG LSSPKIKVIT
     SPNASGKTVY LKQVALLVYM SYIGSYVPGK NVQIGEFDRI LTRIKSNESI NLQMSSYSLD
     LKQLADCVNE SSCKSLVLID ELGNGTDILA GQAIVGAILR YWSSMGENSP HVFFSSHFYE
     MLHCAQSLFG EHNNNIQFLK FDYMFHHEDN SDNVEKMVFL YKLKNGLTSS SHALNILKKL
     PEKYSIEAKQ IFDKVSSIIN TKDLNSENYG KNVEELKILL QSEKAMENFD KAKNTVKQVF
     EMFYNFKLED ENSEESTDKI EKEKEKRALQ LREILKNLKK
//