ID A0A3M7T0A7_BRAPC Unreviewed; 1509 AA.
AC A0A3M7T0A7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=ATP-binding cassette sub-family A member 5-like isoform X1 {ECO:0000313|EMBL:RNA41260.1};
DE EC=3.6.1.15 {ECO:0000313|EMBL:RNA41260.1};
DE EC=3.6.1.3 {ECO:0000313|EMBL:RNA41260.1};
GN ORFNames=BpHYR1_001685 {ECO:0000313|EMBL:RNA41260.1};
OS Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=10195 {ECO:0000313|EMBL:RNA41260.1, ECO:0000313|Proteomes:UP000276133};
RN [1] {ECO:0000313|EMBL:RNA41260.1, ECO:0000313|Proteomes:UP000276133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYR1 {ECO:0000313|EMBL:RNA41260.1};
RX PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA Gomez A.;
RT "Genomic signatures of local adaptation to the degree of environmental
RT predictability in rotifers.";
RL Sci. Rep. 8:16051-16051(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNA41260.1}.
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DR EMBL; REGN01000526; RNA41260.1; -; Genomic_DNA.
DR STRING; 10195.A0A3M7T0A7; -.
DR Proteomes; UP000276133; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:RNA41260.1};
KW Hydrolase {ECO:0000313|EMBL:RNA41260.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000276133};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 897..919
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 940..966
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 978..1005
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1012..1030
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1042..1062
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1097..1119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 423..659
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1189..1430
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1509 AA; 172804 MW; A6D099B7138B65C4 CRC64;
MTFFVQLFGF MKRNIKLRYR NKLLFGLEIY QLIAILAVLI IYTFLFPAKE FGPEEYTPET
IQNNYLDKFL YIYPNSSEIQ KLGSLVESGA RNLKIRYFNN TEKMKEFFES QVDKKYSFTS
LFGIEFEQFP SKYKLYHEYV DNMYDGNKVR YFSNGNECRK SEILTFFEKC SGNIFVYDGT
TFVQYHLNNA LAKFFNKTFP KFQVQLMAKG KYAQETNLLT GISSFYFTLL YTYSLTSFVI
NIVAEKEKKI KELMKMMGML NLSKTAGSAS SVIYSIMSLL YFLVFLPRVF NTELPLWIQW
TLSIIFQFSF SLGIDQLLFI QAKHGSSFPS EFFANPARPN SLSILSCLLM LMVDGALYFI
LTIYFDNVIQ GEYGRAKSPI FFLKPSFWFN RKKNENKTNV LEIDDIQFDS ESVDGDLKNK
KALKIKNLSK KFKNEKGIEY NAIDNLDLTV YSDQITAILG HNGAGKTTLF NILTGLIKPD
DGTASFFDYD ILSDRDLYYV RKMSGVCPQQ NVLYDLLDCY EHLELYAYLK NVPRNQIKDK
IEEILNKVGL IDFKKSRASQ LSGGQKRKLS IAIALIGDPK ILILDEPTSG MDPSSRREIW
SLLQSIRQNR VILLSTHFMD EADILADRKA VITKGKLKCA GSSLYLKNKF GLGYHLNLIA
NQNFDQEPMA ISSMIKKHVQ NSELERFIEK EVSYLLPIDS VANFQSLFED IELNGQSVGI
ESVAISMTTL EEVFLKLADE VHEEKEEDNS SLSELKLSKI KLRPAFLKFI PNLSTIDLAI
NDYATEKNPF LIVNKTNVDH LVQNLIVNNQ LNRQPIKFTE SESNIHATTY AGFIHQDTPK
DIILFYNDSA VFSVPYLVNT FTNLNSRLNG LPLLNATFTS WPQVKKENIS FFDANSFTTL
MILGISLIFP LVSFAAEIVQ DRELKCKSQM RLSGCGFWNY WIPTLIAFLI QSSFLPIILF
LIIYAIPPLN IPEFMPGGAV FSILLTTIIY IPLNLLFVMC LSFMFKKKET TLSFLFTFLL
LLFTIPYLIV TLSQLSSLRT SNILHIVFTL LDPVYAFIGN YNRIAQVYLN QKVEDIKLGK
NSTTVPFGSY FEFHLNFIPL TFIFGLINIL LYGFLLYFIE SFQNGINILD KVTGYKRMIT
PNSDMIQNED SDVKIEREKL KNNNLENCPL SVNELRKDFK NFSLSKQIQN LNNLFSRNCR
NKNLNKIEKK IAVRNLSIGF RHGEIFGLLG TNGAGKTTTI NMICAELKPD AGTIKIKNQP
FNLKNIQLFC QNVSVCPQHN PFWDELTLID HLQIYGSLKK LSDEEIIALS LKFMEMLGIS
EHGYKQVKNL SGGTKRKLAY AITLFGNPEI TLLDEPSTGL DPQSKRKFWN IISETLIMAS
KSAILTTHSM EEAEALCHRI GIMVNGELKC LGSSQYLKEK FGAGYLLELK ISKNKMDEFN
LFINDLFNGQ AIELDNFSDH RLYSVPKKEI KSLARVFKAL ENAKSQDLIG QYDLSQTTLE
QIFIQFAKS
//
