ID   A0A3M8CWT1_9BACL        Unreviewed;       314 AA.
AC   A0A3M8CWT1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase family protein {ECO:0000313|EMBL:RNB80204.1};
GN   ORFNames=EDM56_27745 {ECO:0000313|EMBL:RNB80204.1};
OS   Brevibacillus fluminis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX   NCBI_TaxID=511487 {ECO:0000313|EMBL:RNB80204.1, ECO:0000313|Proteomes:UP000271031};
RN   [1] {ECO:0000313|EMBL:RNB80204.1, ECO:0000313|Proteomes:UP000271031}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 15716 {ECO:0000313|EMBL:RNB80204.1,
RC   ECO:0000313|Proteomes:UP000271031};
RA   Dunlap C.;
RT   "Phylogenomics of Brevibacillus.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RNB80204.1}.
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DR   EMBL; RHHQ01000025; RNB80204.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M8CWT1; -.
DR   OrthoDB; 9771883at2; -.
DR   Proteomes; UP000271031; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR022694; 3-OHacyl-CoA_DH.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48075:SF3; 3-HYDROXYACYL-COA DEHYDROGENASE; 1.
DR   PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   PIRSF; PIRSF000105; HCDH; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000271031}.
FT   DOMAIN          15..189
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   DOMAIN          202..298
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
SQ   SEQUENCE   314 AA;  35693 MW;  37910FA688D20F3A CRC64;
     MYRGEKIMHE GLVEKVGVVG LGAQGWLIAF RCASAHKVTY VYDVSNDSLK KAINNIQNVF
     TTYVNKGLLT REQAEEKYQK IHVCSTLAEC VGDADIVIEA VPENLALKQK IWQEIDVLAP
     QRTLLATNSS SMCSSKIGAD VSRKDRMFNI NLGAPDDMGP PKLDPVEFMY NSETSENTKF
     IAKQFLNSLQ CIIFETHKEI QGFSFNRVWR AVKKECLFLW ANGYSSPEMI DRAWMLEFHT
     TFGPFALMDQ VGLDVVRDIE LNYYFETGDE SDKPPMELEQ MVAKGHLGVK TGKGFYQYPN
     PVYKEAEWLS KKCY
//