ID   A0A3M8D285_9BACL        Unreviewed;      1035 AA.
AC   A0A3M8D285;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Efflux RND transporter permease subunit {ECO:0000313|EMBL:RNB81988.1};
GN   ORFNames=EDM56_24285 {ECO:0000313|EMBL:RNB81988.1};
OS   Brevibacillus fluminis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX   NCBI_TaxID=511487 {ECO:0000313|EMBL:RNB81988.1, ECO:0000313|Proteomes:UP000271031};
RN   [1] {ECO:0000313|EMBL:RNB81988.1, ECO:0000313|Proteomes:UP000271031}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 15716 {ECO:0000313|EMBL:RNB81988.1,
RC   ECO:0000313|Proteomes:UP000271031};
RA   Dunlap C.;
RT   "Phylogenomics of Brevibacillus.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RNB81988.1}.
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DR   EMBL; RHHQ01000021; RNB81988.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M8D285; -.
DR   OrthoDB; 9757876at2; -.
DR   Proteomes; UP000271031; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF24; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000271031};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        330..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        356..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        381..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        426..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        459..481
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        527..544
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        858..877
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        884..904
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        910..934
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        955..975
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        987..1010
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1035 AA;  114836 MW;  2AC2682AE4AC9312 CRC64;
     MIGYIVKKRK ITLLFFVMVA MVGFMSFFQL PRQDYPDIVI NVATVTTVLP GASPEKVEQT
     VTKKLEEKIN ELQGIKSIQS TSSLGVSVIV IETEGDVEPK QKFDELRKKV QDAKADLPND
     AKQPIINDDL NRTFIQSIAV YADTREQVNS LRDLLKTWKD QLRTIPNVAD VTIGGLPEQE
     VRIDVDTQKL QNYGLSWAQV MSAVKTENEK IPLGDLTVSD RTYQLKINET RSIDELNNII
     LSKTPEGFPV YLKDIGKVTM STEQVKTYSY YNGKPSVTLS INAETGSDVP DLQKRVDAMM
     ETLGKTLPAY AHKESIYSQN ERVNELFSEL VREMGIAIVS VLLVCTLGLN VITSLVVAMA
     IPISIAVGLI FLPPMGITLN FISIGALIIV LGILVDDAVV VNDNIERRLS VLREKPFDAS
     VKGAKEVSIS ILTATLATMA SFAPLMFLSG NTGQFIRPMP AIISLTMLAS MIMSLTIIPI
     FREWYEKRSK KSVDSYRKPA GLLGVQIHQL TQWYANRLMP RMLKRPLLTG MVGVMIGTAA
     YGLIPLTPVQ LFPKSDQEVF LVNIRVPVGS SIEKTDKVVG DVSDWVMQQK GVTDVAAYAG
     ESAPKMFSGD TDNGSGIMVG QIVVKYDSHQ MHASDIIEPW RVELKKRFPE ASVVPKELDM
     GPPVGKPIAV RIYGQNIDTL RSISKELKEK ISKVPGTLDI QDDMGFERYT LQFEVNKDLM
     QQKLVNYTEL SRTLRLVSEG IEFSQFDTGN DLIDMKVYLE KTDEDPSMIF QRLTVMNALG
     QQIPLSQLAQ IKPTFSIQKV LHRNLSREVT IYGDVSGRTA TDVMKDILPI VKSTQLPEGY
     RYEIGGETSE QTDIFLDMGK LSIIVVFLIL ILIAMQFYSL TMPVLVMSTI YLAFAGSLIG
     LFITQTPLGF MTMMGVISLS GIVVRNGIVL IEFIEEARHA GTELKEAVIH AGEARLRPIL
     LTSFTAVAGL TPLALTGDVL FKPLAVTIIF GLLFSTMLTL IVVPAFYMVL ARRKAKRLAK
     KAAKRPDLYG EQVEV
//