ID   A0A3M8D9A2_9BACL        Unreviewed;       428 AA.
AC   A0A3M8D9A2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Acyl-CoA thioesterase {ECO:0000313|EMBL:RNB84720.1};
GN   ORFNames=EDM56_21705 {ECO:0000313|EMBL:RNB84720.1};
OS   Brevibacillus fluminis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX   NCBI_TaxID=511487 {ECO:0000313|EMBL:RNB84720.1, ECO:0000313|Proteomes:UP000271031};
RN   [1] {ECO:0000313|EMBL:RNB84720.1, ECO:0000313|Proteomes:UP000271031}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 15716 {ECO:0000313|EMBL:RNB84720.1,
RC   ECO:0000313|Proteomes:UP000271031};
RA   Dunlap C.;
RT   "Phylogenomics of Brevibacillus.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC       {ECO:0000256|ARBA:ARBA00006538}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RNB84720.1}.
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DR   EMBL; RHHQ01000017; RNB84720.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M8D9A2; -.
DR   Proteomes; UP000271031; Unassembled WGS sequence.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR   InterPro; IPR014940; BAAT_C.
DR   InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR   InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR   PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR   PANTHER; PTHR10824:SF4; PROTEIN CBG14567; 1.
DR   Pfam; PF08840; BAAT_C; 1.
DR   Pfam; PF04775; Bile_Hydr_Trans; 1.
DR   PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000271031}.
FT   DOMAIN          16..141
FT                   /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT                   acid N-acetyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF04775"
FT   DOMAIN          207..423
FT                   /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08840"
FT   ACT_SITE        235
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        349
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        384
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ   SEQUENCE   428 AA;  47495 MW;  51EF404FDF86D35A CRC64;
     MLSPAITIFP NEAMIDEEVK ITLSGFESFQ LITVRAIAEG MLGGEFEAES YAVFQADGSG
     NISVANQAPL SGTYNTKDPM GLFWSMDVKK LKFPAKRTLS ALPVFPSFGT VTVMAEVDGH
     VLAETMLTRK YLSEDITYTD VLDDGIVGRL FYHPHRTRPG IIVLGGSEGG IASSSQFAAL
     FASHGYSALA LAYFDFEDLP DGIRNLPLEY VERTIQWMKQ NEYVRDGQVA LFGRSKGAEL
     SLVIGATGTN IHAIVASSPT SVVSIGAWNA ANGSQIYQPQ SSWSYHGVPL PYLQWTEEQC
     RSAMAYIENN ERFDHIHFAG MADEQMAENS TIRLEHAACP LMLISSDDDH YWPSQYHCER
     IVSRLKAFHY PYKVEHLTYA KTGHGIRFPY IPTTRLQLNG GTAQQNAYAS ADSWKHILSF
     LREIFAVE
//