ID A0A3M8DP87_9BACL Unreviewed; 293 AA.
AC A0A3M8DP87;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=NAD(P)-dependent oxidoreductase {ECO:0000313|EMBL:RNB89932.1};
GN ORFNames=EDM56_12325 {ECO:0000313|EMBL:RNB89932.1};
OS Brevibacillus fluminis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=511487 {ECO:0000313|EMBL:RNB89932.1, ECO:0000313|Proteomes:UP000271031};
RN [1] {ECO:0000313|EMBL:RNB89932.1, ECO:0000313|Proteomes:UP000271031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15716 {ECO:0000313|EMBL:RNB89932.1,
RC ECO:0000313|Proteomes:UP000271031};
RA Dunlap C.;
RT "Phylogenomics of Brevibacillus.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNB89932.1}.
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DR EMBL; RHHQ01000008; RNB89932.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M8DP87; -.
DR OrthoDB; 9786703at2; -.
DR Proteomes; UP000271031; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000271031}.
FT DOMAIN 9..165
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 170..290
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 176
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 293 AA; 30770 MW; 535886DC965A98E9 CRC64;
MSIQEKTVIG FIGIGVMGKS MASHLLKAGY SVLVYTRTQQ KADELLAAGA VWKETVAELA
QESDVVITMV GYPSDVEEVY LGEGGIIAHA KPGSHFIDMT TSSPLLAQKI YAQAKAHGMH
ALDAPVSGGD VGAREARLTI MAGGEEEAFE AVKPILAVMG TNIVLQGAAG AGQHTKMCNQ
IAIATNMIGV CEAILYAQKA GLDPERVLTS IEAGAAGSWS LSNLGRRMIA GNFEPGFYVK
HFIKDMTIAL EAAQEMGLMT PGLALSKQLY DELAAQGGEN KGTQALITLL ASM
//
