ID A0A3M8DS11_9BACL Unreviewed; 404 AA.
AC A0A3M8DS11;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=L-2-hydroxyglutarate oxidase {ECO:0000313|EMBL:RNB90245.1};
GN ORFNames=EDM56_06920 {ECO:0000313|EMBL:RNB90245.1};
OS Brevibacillus fluminis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=511487 {ECO:0000313|EMBL:RNB90245.1, ECO:0000313|Proteomes:UP000271031};
RN [1] {ECO:0000313|EMBL:RNB90245.1, ECO:0000313|Proteomes:UP000271031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15716 {ECO:0000313|EMBL:RNB90245.1,
RC ECO:0000313|Proteomes:UP000271031};
RA Dunlap C.;
RT "Phylogenomics of Brevibacillus.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the L2HGDH family.
CC {ECO:0000256|ARBA:ARBA00037941}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNB90245.1}.
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DR EMBL; RHHQ01000007; RNB90245.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M8DS11; -.
DR OrthoDB; 9801699at2; -.
DR Proteomes; UP000271031; Unassembled WGS sequence.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:UniProt.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR43104; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43104:SF2; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000271031};
KW Tricarboxylic acid cycle {ECO:0000256|ARBA:ARBA00022532}.
FT DOMAIN 3..390
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
SQ SEQUENCE 404 AA; 44423 MW; 04906CB69E49B7D8 CRC64;
MYDFAIVGGG IVGLSTAMEL GRRYPHARIL VVEKEDSWAK HQTGHNSGVI HSGIYYKPGS
FKAKFARAGS NSMVQFCQEN DIEHDICGKV IVATKQAELP LMDNLYDRGL ANGLAIHKIS
AEELKEIEPH VNGLGAIRVP MAGIVNYKQV CETFAAIIGR QGGDLRLSTK VVDIREKRGE
VELETTRGTF HTRFLINCAG LHSDRIAKLG GAKADLQIVP FRGEYYELKP EKRYLVKHLI
YPVPNPAFPF LGVHYTRMIG GHVEAGPNAV LSLKREGYKK TDIDLKDLAE VMAFPGFWKL
AGKFWKEGME EYIRSFSKAA FVKSLQELIP EIRSEDLEPA PAGVRAQALK PDGSLVDDFH
IIRGASSIHV CNAPSPAATA SIEIGKAIAE QIPEPQLAKP QAIS
//
