ID A0A3M8DTG3_9BACL Unreviewed; 611 AA.
AC A0A3M8DTG3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:RNB90651.1};
GN ORFNames=EDM56_09165 {ECO:0000313|EMBL:RNB90651.1};
OS Brevibacillus fluminis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=511487 {ECO:0000313|EMBL:RNB90651.1, ECO:0000313|Proteomes:UP000271031};
RN [1] {ECO:0000313|EMBL:RNB90651.1, ECO:0000313|Proteomes:UP000271031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15716 {ECO:0000313|EMBL:RNB90651.1,
RC ECO:0000313|Proteomes:UP000271031};
RA Dunlap C.;
RT "Phylogenomics of Brevibacillus.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNB90651.1}.
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DR EMBL; RHHQ01000007; RNB90651.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M8DTG3; -.
DR OrthoDB; 2985542at2; -.
DR Proteomes; UP000271031; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000271031}.
FT DOMAIN 62..234
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 276..589
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 611 AA; 67302 MW; A05C44AD830415B1 CRC64;
MNKTRQIKQR STLALFLFTL LWVGLVTRLG WIQVVATHHF SDHDVDLVKS AVKQREQTIK
LSSGRGEILD KDGMSLTGKE QRVLAVFPLA RKNLLDEKAF TELARLIGQP EQGLRKQLQM
AKQPEIVRDE KGESVRLTTG QMAQINQLEL PGIVAITVAE RYQENEIAKQ VIGYIHQSPE
LVKERYLQEW KANQMTLATQ VGASGLEKSF DRFLQGVEPD ELSYYVDGQG HLLRGLDLRH
HAGHNQFYPL SVKTTLDRAI QEQLEQVADE SGLNEGAIVV LDVTNADIVA MVSRPQFDPT
KLQASDASWQ NHATKQLAPG SVFKTVVAAA ALGEGIVSPT DRFLCEGEYG KFGFSCWNKA
GHGSITLEEA FAESCNIAFA KIASQVGGDT IAAYAERFGL GAEVGHVTAA LFKQEQFRQI
SGEEAGRVFS PTVSREDEGV LIQTAIGQRD VRMTPLQAAN MMVTIANGGH VYQPRLVSHI
LYRNGGNFFT FESKPSQAKG IDLVTAYKLR RMMRQVVEKG TGKLLQEAKW SVAGKSGTAE
TEKNGEPRNH QWFVGYAPAD EPRYAIAVVA ENRQNGSSHL ATKLFKSVVD HLAFHDHTVS
LGGTAGASLP K
//
