ID   A0A3M8DUW5_9BACL        Unreviewed;       357 AA.
AC   A0A3M8DUW5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Type III polyketide synthase {ECO:0000313|EMBL:RNB91958.1};
GN   ORFNames=EDM56_04180 {ECO:0000313|EMBL:RNB91958.1};
OS   Brevibacillus fluminis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX   NCBI_TaxID=511487 {ECO:0000313|EMBL:RNB91958.1, ECO:0000313|Proteomes:UP000271031};
RN   [1] {ECO:0000313|EMBL:RNB91958.1, ECO:0000313|Proteomes:UP000271031}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 15716 {ECO:0000313|EMBL:RNB91958.1,
RC   ECO:0000313|Proteomes:UP000271031};
RA   Dunlap C.;
RT   "Phylogenomics of Brevibacillus.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RNB91958.1}.
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DR   EMBL; RHHQ01000004; RNB91958.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M8DUW5; -.
DR   OrthoDB; 9786288at2; -.
DR   Proteomes; UP000271031; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877:SF99; 1,3,6,8-TETRAHYDROXYNAPHTHALENE SYNTHASE; 1.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000271031}.
FT   DOMAIN          4..201
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          231..352
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        139
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   357 AA;  38992 MW;  0FB10314E1C94115 CRC64;
     MPHIISVGTA VPIHEVSMEA SMAVSRSLFA DAFPDIDRLL SVFAHSNIRK RHFAAPLEWL
     TEDHPFAEKN KLFIDVACSL GMDAINRCLS RASLSVHDID CLIFNTSTGL STPSIDARLV
     NRLGLRQDVT RIPIWGLGCA GGATGLSRAF DYVRAYPDAV AVLVCVELCG LTFIKQDVSK
     SNLIATSLFG DGAGAVLVAG DAFAAKHGLQ DTPRFLSRKT CTWYDSLDVM GWDVTDAGLK
     VIFSQDIPTL VKKRMRSNVD DFLSEQQLTR AQINHFILHP GGPKVINAYQ QALEIGHEQT
     QHAEEILAEY GNMSSPTVLF VLEKSLQTPW RKREIGLLGA LGPGFSSELI LLEQGGT
//