ID A0A3M8F5V6_9ACTN Unreviewed; 400 AA.
AC A0A3M8F5V6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=ROK family transcriptional regulator {ECO:0000313|EMBL:RNC73122.1};
GN ORFNames=DC095_017830 {ECO:0000313|EMBL:RNC73122.1}, SFRA_015405
GN {ECO:0000313|EMBL:RKM95536.1};
OS Streptomyces xinghaiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1038928 {ECO:0000313|EMBL:RNC73122.1, ECO:0000313|Proteomes:UP000245280};
RN [1] {ECO:0000313|EMBL:RKM95536.1, ECO:0000313|Proteomes:UP000028058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19609 {ECO:0000313|EMBL:RKM95536.1,
RC ECO:0000313|Proteomes:UP000028058};
RX PubMed=25477406;
RA Bekker O.B., Klimina K.M., Vatlin A.A., Zakharevich N.V., Kasianov A.S.,
RA Danilenko V.N.;
RT "Draft Genome Sequence of Streptomyces fradiae ATCC 19609, a Strain Highly
RT Sensitive to Antibiotics.";
RL Genome Announc. 2:0-0(2014).
RN [2] {ECO:0000313|EMBL:RKM95536.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 19609 {ECO:0000313|EMBL:RKM95536.1};
RA Danilenko V.N., Bekker O.B., Vatlin A.;
RT "Genome sequencing of Streptomyces fradiae ATCC 19609.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:RNC73122.1, ECO:0000313|Proteomes:UP000245280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OlgR {ECO:0000313|EMBL:RNC73122.1,
RC ECO:0000313|Proteomes:UP000245280};
RA Danilenko V.N., Bekker O.B., Vatlin A.;
RT "Genome sequencing of Streptomyces xinghaiensis (fradiae) OlgR.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNC73122.1}.
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DR EMBL; JNAD02000006; RKM95536.1; -; Genomic_DNA.
DR EMBL; QFBD02000007; RNC73122.1; -; Genomic_DNA.
DR RefSeq; WP_043460875.1; NZ_QFBD02000007.1.
DR AlphaFoldDB; A0A3M8F5V6; -.
DR OrthoDB; 3189808at2; -.
DR Proteomes; UP000028058; Unassembled WGS sequence.
DR Proteomes; UP000245280; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000835; HTH_MarR-typ.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF12802; MarR_2; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01125; ROK; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000028058}.
FT DOMAIN 19..68
FT /note="HTH marR-type"
FT /evidence="ECO:0000259|Pfam:PF12802"
SQ SEQUENCE 400 AA; 40920 MW; BB29C5EE4C83F837 CRC64;
METPGSQSSL HRANLERVVR AVRLAGSLTQ AEIARTTGLS AATVSNIVRE LRDSGIVQVT
PTSAGGRRAR SVSLSGDAGI VVGVDFGHTH LRVAVGNLAH QVLAEEAEPL DVDASATQGF
DRAEALVKRL IDSTGLGVGK VIGVGLGVPG PIDVDSGALG STAILPGWAG TNPKEELAAR
LGVPVSVDND ANLGALGELV WGTGRGVKDL AYIKVAGGVG AGLVINGHIY RGPGGTAGEI
GHITIDESGP VCRCGNRGCL ETFTAARHVL DLLRTSHGPD LTIERMVQLA REGDPGCRRV
IADVGRYIGT GVANLCNLLN PSRVVLGGDL AEAGELVLLP IRESVARYAI PSAARRLSVL
PGALGGRAEV LGALALVLNE MGDSTLLDGS VATATPAFTR
//
