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Database: UniProt
Entry: A0A3M8FDY7_9ACTN
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Original site: A0A3M8FDY7_9ACTN 
ID   A0A3M8FDY7_9ACTN        Unreviewed;      1588 AA.
AC   A0A3M8FDY7;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   02-DEC-2020, entry version 7.
DE   SubName: Full=Serine protease {ECO:0000313|EMBL:RNC76008.1};
GN   ORFNames=DC095_001905 {ECO:0000313|EMBL:RNC76008.1}, SFRA_002470
GN   {ECO:0000313|EMBL:RKM99088.1};
OS   Streptomyces xinghaiensis.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1038928 {ECO:0000313|EMBL:RNC76008.1, ECO:0000313|Proteomes:UP000245280};
RN   [1] {ECO:0000313|EMBL:RKM99088.1, ECO:0000313|Proteomes:UP000028058}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19609 {ECO:0000313|EMBL:RKM99088.1,
RC   ECO:0000313|Proteomes:UP000028058};
RX   PubMed=25477406;
RA   Bekker O.B., Klimina K.M., Vatlin A.A., Zakharevich N.V., Kasianov A.S.,
RA   Danilenko V.N.;
RT   "Draft Genome Sequence of Streptomyces fradiae ATCC 19609, a Strain Highly
RT   Sensitive to Antibiotics.";
RL   Genome Announc. 2:0-0(2014).
RN   [2] {ECO:0000313|EMBL:RKM99088.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 19609 {ECO:0000313|EMBL:RKM99088.1};
RA   Danilenko V.N., Bekker O.B., Vatlin A.;
RT   "Genome sequencing of Streptomyces fradiae ATCC 19609.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:RNC76008.1, ECO:0000313|Proteomes:UP000245280}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OlgR {ECO:0000313|EMBL:RNC76008.1,
RC   ECO:0000313|Proteomes:UP000245280};
RA   Danilenko V.N., Bekker O.B., Vatlin A.;
RT   "Genome sequencing of Streptomyces xinghaiensis (fradiae) OlgR.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RNC76008.1}.
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DR   EMBL; JNAD02000001; RKM99088.1; -; Genomic_DNA.
DR   EMBL; QFBD02000001; RNC76008.1; -; Genomic_DNA.
DR   Proteomes; UP000028058; Unassembled WGS sequence.
DR   Proteomes; UP000245280; Unassembled WGS sequence.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR043722; DUF5663.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   Pfam; PF18908; DUF5663; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   SUPFAM; SSF50494; SSF50494; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:RNC76008.1};
KW   Protease {ECO:0000313|EMBL:RNC76008.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028058}.
FT   DOMAIN          326..466
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REGION          267..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1566..1588
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1588 AA;  170567 MW;  90C19E9B3C198A7F CRC64;
     MDRGGRERGC HRCGRGGHPM TGPLEAVLRD CTVLLRDGAG KAVGSGFFVA PEQVLTAAHV
     VGAAHGRLRA HWNGITADVS GIGWQEPEEC STEGRWGLPD LALLRLPGAA VAGHPCVLLG
     DGRCGRRLLI EGYTRDLDGG HAPDSVRTEL DTVRPVGRWG VLRLASGIVD DGMSGGPVLD
     LESGQVVGVT KAQRQGPGLG LGGVAVGVDA LAEVRPELFA ENRRFHHRDR RWDFARLNES
     GPVDPADCTR RFLGLVKRVV VRRPAILPPG GSRADIHQMP SVKPQPLGQD NAPGDSEPSD
     SVEPGRRTAT PMNGTFQWAP LRVSWPAVVL SGMPGQGKSW LLNMHAEAVA GDALRRVADE
     PSAWMSVRIP VVLDCAALGR ALPVTVTRET VLDAVVRTVR QECAESGADD AAVAESVVRL
     AYQDGRLLCC LDALDEVAIG DGEKLRRALP VLVEQGNRLI ITSRPSVGLR THTSGLGSHL
     SAEVVGFSPG QVFAFARSWF SGDPQRAGEL EAELLDRPEL ADLARVPLLA AFLCRLAGET
     DRVRVLPGNR VEIYRAVVMG ALSGRWRTPG QQAVAPHSPP DSELRLRALA SAAGRLAGEW
     RTRMDRLPRS RLSAALREHP EYQRLVVGAE CRWEAWQAQR PSGVPTTPPV DAPLWEYTFD
     ALLAHDMNEG GDPVMRFAHP VLAEYCVASY AASLPAPKLR EVVDVHRWFD SHWQEVWPLT
     AGIMAEPDTL VGLFLDGADD AWYEQIMLAA RCVAAAGERV DPGLRQRVLA GLTESARSWR
     SFDRERAVAH LGELVRARLP EAVSAVRELL AGAGEDESSP TQLQAAALLA EAGDPDGLVF
     ARAVLTDQRV PAAYRAWIAR AVVVGGDEEG QQALVTAIGA ARTPGQLRLL VDAVPVEGRA
     GTELAERILR DQRVLPAIRA TLGGVLIRVG GENRIRAALE LAKDPLTVWD VRAQLIADLL
     AVGEDQALPL GLELFDDPGL SQNSRVALVE ALVRRGRLAV LRRAAAMLCN RSFHWDSRRR
     LASAIAGLGP QGTELLLSGV NSPLPLDLKI RHVIALVEVG ECLDLAARLV ADTGAPSWAR
     ARVASALLRR GYTSLPPPVL EQLATDPDPQ HDFQGELIAA MAARGMAGAG DAACGMLSRL
     CATENYPGDR SFMLGLAGAG EDGRQVLIRI AGDASLAEED RALAIIALAD VAPETAAALA
     EAPVVPFSSF ADARVTILLA EKGVIELAGR LARLLEREPA AYRTLYRLLG SSRVTRELVT
     QLVPLGAALT GAPPPPSREA IEIDEEYLRG AGLDWLSRTR FQQLIRWVYR ILEKRVGLKI
     AAFLTESQLV EFERLEDEQP SLEFLATRAA GYPELVVGQA ADLQDDIRQG KVRPPDPDSL
     DDAPVLQRLS YTASLLSEWL AAIEQNPNAG LSFLAGNHRV LLTAEAQALL QLAATLTHRC
     NPHEGMTFVV ARGTANGVQE VLELMQDPDR LQQVLAGYLN QGDGTTLLFA ALAGILFARP
     ASPVPHFYGA LGAAMQGNRD LSIDLMRISG ATASPDQRQE GTATLNTIAA RFGWDEGTVV
     ALREALLSPR SETADTDTDD EGEGRDGH
//
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