ID A0A3M8FNE2_9BACT Unreviewed; 447 AA.
AC A0A3M8FNE2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Thymidine phosphorylase {ECO:0000313|EMBL:RNC79478.1};
DE EC=2.4.2.4 {ECO:0000313|EMBL:RNC79478.1};
GN ORFNames=ED557_15510 {ECO:0000313|EMBL:RNC79478.1};
OS Balneola sp.
OC Bacteria; Balneolota; Balneolia; Balneolales; Balneolaceae; Balneola.
OX NCBI_TaxID=2024824 {ECO:0000313|EMBL:RNC79478.1, ECO:0000313|Proteomes:UP000280416};
RN [1] {ECO:0000313|EMBL:RNC79478.1, ECO:0000313|Proteomes:UP000280416}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bin6 {ECO:0000313|EMBL:RNC79478.1};
RA Zheng Q., Wang Y., Jiao N.;
RT "Metagenomics and metaproteomics analyze the interactions between
RT Synechococcus and associated heterotrophic bacteria in one oligotrophic
RT Synechococcus culture.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the thymidine/pyrimidine-nucleoside
CC phosphorylase family. {ECO:0000256|ARBA:ARBA00006915}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNC79478.1}.
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DR EMBL; RHLJ01000007; RNC79478.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M8FNE2; -.
DR Proteomes; UP000280416; Unassembled WGS sequence.
DR GO; GO:0004645; F:1,4-alpha-oligoglucan phosphorylase activity; IEA:InterPro.
DR GO; GO:0016154; F:pyrimidine-nucleoside phosphorylase activity; IEA:InterPro.
DR GO; GO:0009032; F:thymidine phosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006206; P:pyrimidine nucleobase metabolic process; IEA:InterPro.
DR GO; GO:0006213; P:pyrimidine nucleoside metabolic process; IEA:InterPro.
DR Gene3D; 3.40.1030.10; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR Gene3D; 3.90.1170.30; Pyrimidine nucleoside phosphorylase-like, C-terminal domain; 1.
DR InterPro; IPR000312; Glycosyl_Trfase_fam3.
DR InterPro; IPR017459; Glycosyl_Trfase_fam3_N_dom.
DR InterPro; IPR036320; Glycosyl_Trfase_fam3_N_dom_sf.
DR InterPro; IPR035902; Nuc_phospho_transferase.
DR InterPro; IPR036566; PYNP-like_C_sf.
DR InterPro; IPR013102; PYNP_C.
DR InterPro; IPR018090; Pyrmidine_PPas_bac/euk.
DR InterPro; IPR017872; Pyrmidine_PPase_CS.
DR InterPro; IPR000053; Thymidine/pyrmidine_PPase.
DR NCBIfam; TIGR02644; Y_phosphoryl; 1.
DR PANTHER; PTHR10515; THYMIDINE PHOSPHORYLASE; 1.
DR PANTHER; PTHR10515:SF0; THYMIDINE PHOSPHORYLASE; 1.
DR Pfam; PF02885; Glycos_trans_3N; 1.
DR Pfam; PF00591; Glycos_transf_3; 1.
DR Pfam; PF07831; PYNP_C; 1.
DR PIRSF; PIRSF000478; TP_PyNP; 1.
DR SMART; SM00941; PYNP_C; 1.
DR SUPFAM; SSF52418; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR SUPFAM; SSF47648; Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain; 1.
DR SUPFAM; SSF54680; Pyrimidine nucleoside phosphorylase C-terminal domain; 1.
DR PROSITE; PS00647; THYMID_PHOSPHORYLASE; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:RNC79478.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000280416};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:RNC79478.1}.
FT DOMAIN 349..423
FT /note="Pyrimidine nucleoside phosphorylase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00941"
SQ SEQUENCE 447 AA; 48755 MW; 635D7BE846BFBD86 CRC64;
MSSKYNIVSL IRKKRQGESL TSDEIHYLVH AYTDHTIQDY QMSAFLMAAF LKGLNMEESA
ALTDSMLESG IVVDLSDIPG VKVDKHSTGG VGDKLSLILA PVVASAGVPV PMISGRGLGH
TGGTLDKLES IPGFYTDMDL KRYHDIISKH NLVLAGQTKE IAPADKKLYA LRDVTATVES
IPLIAGSIMS KKLAEGIDAL VLDVKYGSGA FMKDLDSAIE LAEELVGIGD RFNKKTIAYL
TNMNQPLGFK IGNWLEVEEC VEALNGEGPE DIVKLSNLLS GTMIYLGEKA GSVEEGIKKS
EEQIENGKAF QKWIDIVEEQ GGDSSLIKNL KNYPKSGYEF SLKSQKSGFI NAMDSYQIGM
ASLELGAGRR EKEDVIDPTA GIILNKKVGD KIEEGETILT GYTNKPAMIE IVTEELFQSV
EIRNERPKPE PLVTHICDSQ GTRAFEL
//
