ID A0A3M8Q8P0_9GAMM Unreviewed; 326 AA.
AC A0A3M8Q8P0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Dihydrodipicolinate synthase family protein {ECO:0000313|EMBL:RNF51644.1};
GN ORFNames=EBI00_07065 {ECO:0000313|EMBL:RNF51644.1};
OS Marinomonas hwangdonensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinomonas.
OX NCBI_TaxID=1053647 {ECO:0000313|EMBL:RNF51644.1, ECO:0000313|Proteomes:UP000280507};
RN [1] {ECO:0000313|EMBL:RNF51644.1, ECO:0000313|Proteomes:UP000280507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HDW-15 {ECO:0000313|EMBL:RNF51644.1,
RC ECO:0000313|Proteomes:UP000280507};
RX PubMed=22021582; DOI=10.1099/ijs.0.036582-0;
RA Jung Y.T., Oh T.K., Yoon J.H.;
RT "Marinomonas hwangdonensis sp. nov., isolated from seawater.";
RL Int. J. Syst. Evol. Microbiol. 62:2062-2067(2012).
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNF51644.1}.
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DR EMBL; RIZG01000003; RNF51644.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M8Q8P0; -.
DR OrthoDB; 6142028at2; -.
DR Proteomes; UP000280507; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF74; BLL4423 PROTEIN; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000280507}.
FT ACT_SITE 142
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 170
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 215
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 326 AA; 35358 MW; 4CA04EA4641FE538 CRC64;
MMSNDVFDVS VFNGIMPALM TPCKADRTPD FDNLVKKGKE MMAAGMSAVV YCGSMGDWPL
LTDAERMEGV ERLVNAGIPV VVGTGAINTK SAVALAAHAE KVGAAGLMVI PRVLSRGSVI
AAQKHHFKAI LDAAPSIPAI IYNSPVYGFE TRADLFFALR TEHKNLVGFK EFGSKEALRY
AAENITSQDD DVLLMVGVDT AVYHGFVKCG AVGAITGIGT ALPKEVLLLA NLCRLAAKGN
AEARVRAQEL EEAFSVLASF DEGPELVLFF KYLLVLNGEE AYRLHFNETD ELNAAQRRYC
EEQYALFKDW FADWATQGGV IDTCKS
//
