ID A0A3M8SUJ3_9GAMM Unreviewed; 504 AA.
AC A0A3M8SUJ3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Probable periplasmic serine endoprotease DegP-like {ECO:0000256|ARBA:ARBA00013958};
DE EC=3.4.21.107 {ECO:0000256|ARBA:ARBA00013035};
DE AltName: Full=Protease Do {ECO:0000256|ARBA:ARBA00032850};
GN ORFNames=EER27_04035 {ECO:0000313|EMBL:RNF84969.1};
OS Lysobacter psychrotolerans.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Lysobacter.
OX NCBI_TaxID=1327343 {ECO:0000313|EMBL:RNF84969.1, ECO:0000313|Proteomes:UP000267049};
RN [1] {ECO:0000313|EMBL:RNF84969.1, ECO:0000313|Proteomes:UP000267049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZS60 {ECO:0000313|EMBL:RNF84969.1,
RC ECO:0000313|Proteomes:UP000267049};
RA Luo Y., Sheng H.;
RT "Lysobacter cryohumiis sp. nov., isolated from soil in the Tianshan
RT Mountains, Xinjiang, China.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Might be efficient in the degradation of transiently
CC denatured and unfolded proteins which accumulate in the periplasm
CC following stress conditions. {ECO:0000256|ARBA:ARBA00002610}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNF84969.1}.
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DR EMBL; RIBS01000002; RNF84969.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M8SUJ3; -.
DR OrthoDB; 9758917at2; -.
DR Proteomes; UP000267049; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011782; Pept_S1C_Do.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; TIGR02037; degP_htrA_DO; 1.
DR PANTHER; PTHR22939:SF130; PERIPLASMIC SERINE ENDOPROTEASE DEGP-LIKE; 1.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:RNF84969.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000267049};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..504
FT /note="Probable periplasmic serine endoprotease DegP-like"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038447321"
FT DOMAIN 294..346
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 97..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 134
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 164
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 238
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
SQ SEQUENCE 504 AA; 51024 MW; F7E5808354955069 CRC64;
MNRPLRALAL VSAIALSVPA ACTAQSPVAA NPIAPPPAAA PAAPLVTGLP DFTALVQKVG
PAVVSVSAQS APRRVARGQM PDEGDIPEIF RRFFGPEGMP MPGDPNGPRG PRRGSSLGTG
FLISDDGYVL TNHHVVDGAD EVSIRLSDRR EFTAKVVGSD QATDVALLKI DAKGLPSLRV
ANASLTRAGQ WVIAIGSPFG LEHSVTAGIV SAVGRSTGSG QQYVPFIQTD VAINQGNSGG
PLLNTAGEVV GINSQIFSNS GGYMGVSFAI PIDLAMNAAE QLRATGRVSR GQLGVQVQQI
TADTARGLGL PDSRGALVAD VVAGSPAEKA GIERMDVIRA FNGRPVDESS GLPPLVGAVA
PGSRAKVSVI RAGKPIELDV VVGELDAPIA SAPPAGSGNT APAAPGRGNA LGLVAQDLTA
VERQRLGLAS GEGVRLARIT GDAAGEAGLQ PGDVILAVGR NSVGTAAALD RALASVQPDQ
TVMLLIRRGN GTQFVAVTPD PQAG
//
