ID   A0A3M9MIT4_9MICO        Unreviewed;       745 AA.
AC   A0A3M9MIT4;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=MMPL family transporter {ECO:0000313|EMBL:RNI24743.1};
GN   ORFNames=EFY87_03340 {ECO:0000313|EMBL:RNI24743.1};
OS   Flexivirga caeni.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermacoccaceae;
OC   Flexivirga.
OX   NCBI_TaxID=2294115 {ECO:0000313|EMBL:RNI24743.1, ECO:0000313|Proteomes:UP000271678};
RN   [1] {ECO:0000313|EMBL:RNI24743.1, ECO:0000313|Proteomes:UP000271678}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BO-16 {ECO:0000313|EMBL:RNI24743.1,
RC   ECO:0000313|Proteomes:UP000271678};
RA   Im W.T.;
RT   "Draft genome of Simplicispira Flexivirga sp. BO-16.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RNI24743.1}.
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DR   EMBL; RJJQ01000002; RNI24743.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M9MIT4; -.
DR   OrthoDB; 7051771at2; -.
DR   Proteomes; UP000271678; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000271678};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        33..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        214..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        259..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        314..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        344..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        415..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        557..574
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        581..602
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        622..643
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        670..692
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        698..720
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          267..365
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          374..396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   745 AA;  77045 MW;  368BABFDCE0440CB CRC64;
     MTTERTTSTD PHARPATADG ASGPPRHTGL ARLGAWSASH LGIVLALWLV VLAGFGAFAP
     KVETALSGAG WQDSGSQSVQ ARDVIQHDFA GMGSTALQVV VHDGTGPIAK DPAARRVIAQ
     VESTLKADPR VSTVVAPRPG VSLSRDGTTA IVQAGAAQDA NTMVRAADDL TAPLSRLATS
     TISVNLTGSS ALWSDFNKVN HSAMIKSEVL SWPVTLIVLV LAFGSLVAAG LPLMLTMVGL
     LTAAGALVIA THLAPVSVWA LNFAMMFALA LGIDYALFLV VRYRSALHHR GAQPGDRRTA
     VEAVAETMGT AGKAIAFSGV TVLVSLSTVL LVPSPAFRSM ALGIMLSVVA VLAATLTLLP
     AVLGKLGTKI DAGRLRRPGS DRRPGRHTTT QGTTHRRGVE QLMHRWGALL HRRPWAAGAL
     ALAVLALLAA PVLGLRTGMP SISIIPANQS ARAGYQQVTA AFGQGAPGTL QVITPTPDAG
     AARAALAHDR GIAATVPAGA NDGRTMLLAI PTTDASAPAT GATIDRIRTE LPHGSLVGGA
     AAENHDLEKA LSAKTPVVFA LLIGLGFLLL LIALGSPLIA FVGTITNLAS IGAAFGVAKL
     IFGDGHLSGL LGFQSQGFVD AWAPLFFGAM LTGVAMDYTL FLLSAAREQY DATGDPQHAM
     REALRTSGRV VVAAAGVMVA VFLTFALSGP LAPKEMGIIL AVAVFLDALC IRLILLPVVL
     RLTGHRAWRA PTWLAKVLPA VRFTH
//