ID A0A3M9Y346_9PEZI Unreviewed; 876 AA.
AC A0A3M9Y346;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Calcium permeable stress-gated cation channel 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=D7B24_000586 {ECO:0000313|EMBL:RNJ54296.1};
OS Verticillium nonalfalfae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=1051616 {ECO:0000313|EMBL:RNJ54296.1, ECO:0000313|Proteomes:UP000267145};
RN [1] {ECO:0000313|EMBL:RNJ54296.1, ECO:0000313|Proteomes:UP000267145}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VnAa140 {ECO:0000313|EMBL:RNJ54296.1,
RC ECO:0000313|Proteomes:UP000267145};
RA Stajich J.E., Kasson M.T.;
RT "Genome sequence of Verticillium nonalfalfae VnAa140.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNJ54296.1}.
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DR EMBL; RBVV01000109; RNJ54296.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M9Y346; -.
DR STRING; 1051616.A0A3M9Y346; -.
DR OrthoDB; 366603at2759; -.
DR Proteomes; UP000267145; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF83; CALCIUM PERMEABLE STRESS-GATED CATION CHANNEL 1; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 30..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 539..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 595..616
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 664..681
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 702..720
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 726..747
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..202
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 222..432
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 443..719
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 304..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 819..876
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..335
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 780..795
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 828..862
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 876 AA; 98846 MW; C06C53689872C3F4 CRC64;
MDDLFDYATK KKTNETCNGA DYLRPRNVDI TVQLGLSLVL GISAFTTFCI LRPRWSSLYA
ARKRRLDPTI GLPALPDTFF GWIPGLFRVT EEQVLASAGL DAFVFLSFFK MSIRLLSIMA
FFAYAVLLPV NRHFMSDSGH HGKHPSTTVL HTVYGQANLD GAFEPSHGVG TVAKNNGKAH
LWAWLVFTYF FTALTIYIVN KETFRVIRVR QEYLGTQSTI TDRTFRLTGL PSNLKDEQKI
KELIEGLEIG QVETVSLCRN WKELDGLVAQ REAMLRKLEE AWSVYLGKQS ALPKSIQRLR
SNRIEDEENQ GSGSGDSDEQ EDAGENGRLL SHEDIRPELI ERQRPSLTLR YGLLGLRTRK
TDAIDYYEEK LRRLDDRIIA SRKKTPAAAS TAFVTMDSIA ACQMAIQARI DPRPGQLLTK
PAPSPSDVIW ANTYTPRGVR RLRSWVITIF VTLLSLVWIG SVASLAGLLT ICNLKKWFPN
VVATLDDLPV LRALIETGLP TLLVSLLNVA VPYLYDFLSY QQGMISKGDV ELSIISKNFF
FSFFNIFIVF AISSTAINIF QVVGRVQDGL RDTGAFARFI AGQINDLSFF YTNFIMLQGL
GLFPFRLLEV GSVLLYPIYR MGAKTPRDFA QIMSPPVFSY GFYLPTALLV FILCLVYSVI
QYGYLVLTVG LVYFTFGYFT YKYQLLYAMD QPQHATGGAW RIICNRVVLG LFVFQVVMIS
EMALESAFIQ SVLTFPLIFL TIWYNYYFSR RFVPLTYFIA LRSIVPEAGT GEEAVADDED
FDGPRPSHGL LRRGSTIDED KEKGMKFVNP SLTYRLENPW IYQDPPPTQP SEAESQEQLV
DIQASPDQGL NHTGTSESSL SLGDAHIWRD NSENRA
//
