ID A0A3M9Y4P4_9PEZI Unreviewed; 1268 AA.
AC A0A3M9Y4P4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 22-FEB-2023, entry version 14.
DE RecName: Full=Clustered mitochondria protein homolog {ECO:0000256|HAMAP-Rule:MF_03013};
DE AltName: Full=Protein TIF31 homolog {ECO:0000256|HAMAP-Rule:MF_03013};
GN Name=CLU1 {ECO:0000256|HAMAP-Rule:MF_03013,
GN ECO:0000313|EMBL:RNJ55241.1};
GN Synonyms=TIF31 {ECO:0000256|HAMAP-Rule:MF_03013};
GN ORFNames=D7B24_008854 {ECO:0000313|EMBL:RNJ55241.1};
OS Verticillium nonalfalfae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=1051616 {ECO:0000313|EMBL:RNJ55241.1, ECO:0000313|Proteomes:UP000267145};
RN [1] {ECO:0000313|EMBL:RNJ55241.1, ECO:0000313|Proteomes:UP000267145}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VnAa140 {ECO:0000313|EMBL:RNJ55241.1,
RC ECO:0000313|Proteomes:UP000267145};
RA Stajich J.E., Kasson M.T.;
RT "Genome sequence of Verticillium nonalfalfae VnAa140.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: mRNA-binding protein involved in proper cytoplasmic
CC distribution of mitochondria. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBUNIT: May associate with the eukaryotic translation initiation
CC factor 3 (eIF-3) complex. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SIMILARITY: Belongs to the CLU family. {ECO:0000256|HAMAP-
CC Rule:MF_03013}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNJ55241.1}.
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DR EMBL; RBVV01000082; RNJ55241.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M9Y4P4; -.
DR STRING; 1051616.A0A3M9Y4P4; -.
DR OrthoDB; 927222at2759; -.
DR Proteomes; UP000267145; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007005; P:mitochondrion organization; IEA:UniProtKB-UniRule.
DR GO; GO:0051640; P:organelle localization; IEA:UniProt.
DR CDD; cd15466; CLU-central; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR HAMAP; MF_03013; CLU; 1.
DR InterPro; IPR033646; CLU-central.
DR InterPro; IPR025697; CLU_dom.
DR InterPro; IPR028275; CLU_N.
DR InterPro; IPR027523; CLU_prot.
DR InterPro; IPR023231; GSKIP_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12601:SF6; CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG; 1.
DR PANTHER; PTHR12601; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3; 1.
DR Pfam; PF13236; CLU; 1.
DR Pfam; PF15044; CLU_N; 1.
DR Pfam; PF12807; eIF3_p135; 1.
DR Pfam; PF13374; TPR_10; 2.
DR Pfam; PF13424; TPR_12; 1.
DR SUPFAM; SSF103107; Hypothetical protein c14orf129, hspc210; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51823; CLU; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_03013};
KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_03013};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 337..581
FT /note="Clu"
FT /evidence="ECO:0000259|PROSITE:PS51823"
FT REPEAT 999..1032
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 167..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 622..660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 886..925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1201..1268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1215..1235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1268 AA; 140278 MW; 67EE758BA646E1F8 CRC64;
MSSEKNEVPA GSIPAADEVA PQDDAGQDAA IAENHVDQEE HAAEALINLT ISLPQEPYSM
TILVSPQEQV HEVRQSIIDL PAAFRYTCFH LEHNGERVND FIPMSEVPGI AENPNVTLVE
DPYTEKEARI HLVRIRELIG GAGDRADVVQ GILPGLSLLD SIDVTAKHGS ERNEDQPPAE
QPETLAESTF SSAASISHLL PPPPDDAPKT IKTITLSSWN PPPCHLKQRG HLLYLIITTN
EGEQFQVTAH VGGFYVNKSS NSKFDPLPRP APKGQSAHSL LSLLELISPS FESSFKALQE
FNNRKDPLAT FQIANAIPAA PWIVPSTTSP HCTHLSDPTR SQETYLIAGV DNTDTLRDWN
EEFQSAKELP KETVQDRVFR ERLLSKLFAD YNDAATRGAV LVARGEIPPL NPTECKDAQI
FVYNNVFFSF GADGVGTFTS EGGDEAARVA TGKDVAGVRL VNQLDVDGLF TTATVVVDYL
GKRIVGQSIV PGIFKPREPG ENQIDYGAVE GKDIVAADDR FVSVFEKLSR ALRVKKHPVW
DKESKRIDLE ASVETKGLMG TDGRKYVLDL YRVTPLDVPW LEASAEKGEF PEYPHRMTVL
RPELVESFGR KKMKEWVDEQ LAQRAQSKQD STDDATKQAS TADSTGESTE AQATSEKEKD
RIDLSQFQFA LNPDAFSGQL PQTPDEKAEL KADEKDVRVA CEYLTDRVIP DLVRELQDCD
ISFPMDGQAL SRLLHKRGIN VRYLGRIASL STDPRLQCLR DIAIQDMVAR SFKHVISSFL
RETPSPLASS CVAHLLNCLL GAELNPKPVA DVDPTMKALY SDLDTSYESV TPQILRARIS
EETHRRYRFK LDGEWYKSIK PLQTLREISL KLGLQLQAKE YLFSKTDSTE APTEAKPADA
TANGQLNGES KKKNKKKNRD ASPAAVATTG APCTFSADDV INIVPVVKHS CPRSALAEEA
LEAGRISIMQ SQKKLGQELL LESLSLHEQI YGILHPEVAR VYNTLSMLYY QLDEKEAAVE
LSRKAIVVSE RTVGVDSAET LLNYLNLSLF LHQTGDSQGA LSYAKHALQL WKIIYGPDHP
DSITTINNGA VMLQHLKAYH ESRLWFEESL RVCEKVFGKS SINAATLLFQ LAQALALDQD
SKGAVKRMRE SYNIFLSELG ADDKNTKEAE SWLEQLTQNA VSIAKHAKDM QTRRLRTGIK
FSPRGAPFEA DAPSAVASTS RQTQLDGSSQ MDSRSIDELI KFIEGNDQQT NKSSKRPSRG
NPKRRGKA
//
