ID A0A3M9Y6G2_9PEZI Unreviewed; 1760 AA.
AC A0A3M9Y6G2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN ORFNames=D7B24_008367 {ECO:0000313|EMBL:RNJ55582.1};
OS Verticillium nonalfalfae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=1051616 {ECO:0000313|EMBL:RNJ55582.1, ECO:0000313|Proteomes:UP000267145};
RN [1] {ECO:0000313|EMBL:RNJ55582.1, ECO:0000313|Proteomes:UP000267145}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VnAa140 {ECO:0000313|EMBL:RNJ55582.1,
RC ECO:0000313|Proteomes:UP000267145};
RA Stajich J.E., Kasson M.T.;
RT "Genome sequence of Verticillium nonalfalfae VnAa140.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNJ55582.1}.
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DR EMBL; RBVV01000074; RNJ55582.1; -; Genomic_DNA.
DR STRING; 1051616.A0A3M9Y6G2; -.
DR OrthoDB; 25601at2759; -.
DR Proteomes; UP000267145; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd07589; BAR_DNMBP; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR22834; NUCLEAR FUSION PROTEIN FUS2; 1.
DR PANTHER; PTHR22834:SF20; NUCLEAR FUSION PROTEIN FUS2; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 998..1220
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 1..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 153..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..638
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..845
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 865..914
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 926..947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 963..994
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1075..1107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1492..1560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1575..1682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 661..688
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 10..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..71
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..527
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..572
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 727..741
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1078..1098
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1494..1508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1524..1560
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1575..1599
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1621..1649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1760 AA; 195026 MW; A901423438D5C575 CRC64;
MEDGFREEED PLGTDTLRTA SDRGRAHAHH AHHHPTHAVD GHHSYVKHDD DDDARYQDSL
HRQHQHQHHT QAHTEYTYPV YDEPPELSPT DTPYTPGSRP VATQTTFDID SLDPFAASVA
FDSPTGDGID GGIGSHVVAV VTPDDFYRDY RSASSTHYHH QHSRQPSSSS ERAPMATSVP
RPRDPASLRS NGNGTTAKHP PMPTALNGLR TATRSVSAPI DPSSTTGPKR LNNAARQPSV
KDLTKKFDQG PPTAIPRLPV RTGIPSRPNK PATSSDKPLP TAPVGQRQTS YSTLRTSVDR
NLTPDSARAT RSTQRTKFVA EDQTSNNSQS FASRIGKPRT PVALNAQPSQ STPTVSQKHS
FQPTTASPNA SPMIPQSQTL LFGEILPDQR DNHTLGHGIE GSGSRPRRTS ESNVSSIRSA
HQRTLSDPDL IEPSSPTDWY RIANDDTNGL QPQQTRHLKS HVRAQSDTPS IIPRKPPPPA
VGATERSRAV SPSTRLPISV RRLASPSPSL STSSPSGGNS RANSPSNLHR IKPHGRPSRA
ASAQGYRSKT PTQSTRRAPP QGLTTPSNNG RLTPYGGVPA PKLSPPLRSS RPRQSVATAT
TTSSRMKALE RARSPHYHAT RNAQKSTEAP TRRRKISVGP VDFEQRREHI RLAYTKSIRD
SQAREARLQA AERRKKELEV AARTKAALTA SQAAANQDER TAHDHVAASD LDSRLLSPLK
IPTGTECSEP SPATLSPQPD VVKESPTLGI PGSFPAGSPA IEFEEAPPSA ISMATDVTEF
DDEPQVFPLV QPDHGATSSG LGLALPDMPG SFTVSEADVP EDDERLGART PPFEAPSTDE
HVTHHDSFPQ EAVEDEQVSI KIAATDVPQQ TSEEAPHSTP KYVDSEQMAE PQPDTASNLE
AYKDEYEPLP YSSPSLETTV KILHRESDQF TKPERSSIAD EPHDDSYHMS LDQHEARAFR
TFVRQEQSQR ESDKTHSPSR QDKDQSVPIT KEQRRLQQRR NVIKELVDTE MVFVRDMNIV
EEIYKGTAEA CPKLDGKTSK NIFRNVDEIV AFHTAFLVQL KDAVAAVYIP QGRRSSAPKE
ASIKSNSTGS NSGAQSQTES DDAKDRTTTL GPLFQLNAEK MKIAHEGFLR NSDLAAKRLI
QIQQDPTVQV WLNECHEVAK DLTAAWDLDS LLIKPMQRLT KYPNLILTIL QHTPPDHPDR
PALVAAKDTL EVAIIEINKT KKNFELVGQI VGRKRKESDV KAGFARAFGK RVDRLQATST
RIPEDPEYAK LHEKFGDDYL RLQVVLRDVE FYTRQVTSYV HEFLQYLSSM ELVMRLQPGS
YPEIESKWVQ FNVSMRDIEK VALDQHLAQV RKQVIEPFEL VIKAYGNPSL AMKKREKRRL
DFERAEQIRK GGKTLDPKLK ELVEQYDALN DTLIKELPQL SALTEKVGKI CLENLVNIQA
KWYSIWKDKV KVVLADTSSL PEMPDVVSIF QHDFKFAQDQ LDTIGILHPE YKGRASQSTI
TTRASTEDGT PRNRPRPAEL TPRNRGRSMN SEQTPALPTP EFKRNSGQFT LSPTSTVPSP
HQYYYRDYYT NANATASGSG SGSGQRPSVP PSPRTEDSSP SLRAAGGYPL ARPSTGRSYD
SGGLPRESSD SSLHNRRDSN STYNSGYPAT EPKRYSGLFH SALPLPDSAE ESQRSSRASS
RERFPESSNY NVLWLAASLF EFNIETTKNE AGYPYLTYQA GEIFDVIAEK GELWLAKNQD
DPREQVGWIW SKHFARLADS
//
