ID A0A3N0C218_9SPHI Unreviewed; 620 AA.
AC A0A3N0C218;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Divalent metal cation transporter MntH {ECO:0000256|HAMAP-Rule:MF_00221};
GN Name=mntH {ECO:0000256|HAMAP-Rule:MF_00221};
GN ORFNames=D7004_01055 {ECO:0000313|EMBL:RNL56508.1};
OS Pedobacter jejuensis.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=1268550 {ECO:0000313|EMBL:RNL56508.1, ECO:0000313|Proteomes:UP000274046};
RN [1] {ECO:0000313|EMBL:RNL56508.1, ECO:0000313|Proteomes:UP000274046}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TNB23 {ECO:0000313|EMBL:RNL56508.1,
RC ECO:0000313|Proteomes:UP000274046};
RA Cho Y.-J., Cho A., Kim O.-S.;
RT "Genome sequencing of Pedobacter jejuensis TNB23.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: H(+)-stimulated, divalent metal cation uptake system.
CC {ECO:0000256|HAMAP-Rule:MF_00221}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_00221};
CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_00221}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NRAMP family. {ECO:0000256|HAMAP-
CC Rule:MF_00221}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_00221}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNL56508.1}.
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DR EMBL; RBEE01000002; RNL56508.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3N0C218; -.
DR OrthoDB; 9787548at2; -.
DR Proteomes; UP000274046; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR CDD; cd00293; USP_Like; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR HAMAP; MF_00221; NRAMP; 1.
DR InterPro; IPR001046; NRAMP_fam.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR006016; UspA.
DR NCBIfam; TIGR01197; nramp; 1.
DR NCBIfam; NF037982; Nramp_1; 1.
DR PANTHER; PTHR11706:SF101; MANGANESE TRANSPORTER SMF1; 1.
DR PANTHER; PTHR11706; SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER; 1.
DR Pfam; PF01566; Nramp; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00447; NATRESASSCMP.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_00221};
KW Ion transport {ECO:0000256|HAMAP-Rule:MF_00221};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_00221};
KW Symport {ECO:0000256|HAMAP-Rule:MF_00221};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_00221};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_00221};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_00221}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT TRANSMEM 59..82
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT TRANSMEM 102..125
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT TRANSMEM 163..182
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT TRANSMEM 202..221
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT TRANSMEM 242..272
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT TRANSMEM 292..318
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT TRANSMEM 339..357
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT TRANSMEM 363..384
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT TRANSMEM 404..422
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT TRANSMEM 434..457
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00221"
FT DOMAIN 487..620
FT /note="UspA"
FT /evidence="ECO:0000259|Pfam:PF00582"
SQ SEQUENCE 620 AA; 68372 MW; D1F8A9DC04A41F6A CRC64;
MAKTESLSEV HQSVNTDKRK GWRRILSFIG PAYLISVGYM DPGNWATDLA GGSKFGYQLI
WVLLMSNLIA LLLQSLSARL GIVRGLDLAQ ASKHAYPKWV NIPLFGLAQT AIVACDLAEI
IGMAIGLQLL FGLPLIWGIS ITIFDTILLL FLLNRGMRAM EGFIVSMVFI VGISFLVEMF
IVEPSLKEVV KGFEPSLLSG DALYIAIGII GATVMPHNLY LHSSLVQTRK IERTNKGMKE
AIKFNFIDTA VALNLAFFVN AAILILAAAA FFRNGLHEVA EIQDAHKLLS NIFGNVAPTL
FAIALIAAGQ SSTVTGTLAG QIIMEGHINL RIQPWLRRLI TRLLAIIPAF FTILYYGDGA
LGSLLVLSQV VLSLQLGFAV IPLIHFTSDK KLMKDFAIKT WMKVWAWGSA FLIISLNVKL
VIEEISGWAK DANTWWIYVF VFPAVVLVVL LLLYVFLHPL INKGNLQRQM VPHGNALDIG
KIEKISYERI GIAVDFSTND RNTIRHALIQ GGKDAHYYLI HVVETAAARY HGDIVMDHET
QSDANNLEKY KINLADLGYD ATVFIGFGGT AKAIADISNK NKFELLVMGA HGHKGLKDLI
FGTTVDSVRH KVNIPVLIIR
//
